Ortho Pharmaceutical Corporation

Other

Michele Ann Weidner-Wells

Ramesh M Kanojia

Sigmond G Johnson

James P Demers

Dieter H Klaubert

Roger F Frechette

Stephanie A Fraga

The invention relates to triphenylalkyl antibacterial compounds of the general formula: ##STR1## pharmaceutical compositions containing the compounds, and methods for their production and use. These compounds are effective in inhibiting the action of a bacterial histidine protein kinase and are thus useful as anti-infective agents against a variety of bacterial organisms, including organisms which are resistant to other known antibiotics.

Triphenylalkyl antimicrobial agents

The invention relates to benzoxazine and pyrido-oxazine antibacterial compounds of the general formula: ##STR1## wherein the moiety Q is a fused phenyl or fused pyridyl moiety as herein described, pharmaceutical compositions containing the compounds, methods for their production and their use in treating bacterial infections.

Benzoxazine antimicrobial agents

Growing community of inventors

Somerville, NJ, United States of America

Michele Ann Weidner-Wells