Galderma Research & Development

Galderma S.a.

Michel Poncet

Christian Loesche

Denis Gross

Michael Graeber

Jean Jacovella

Alexandre Kaoukhov

Jean-Paul Chappuis

Philippe Briantais

Laurence Salin

Marie-line Abou-Chacra Vernet

Marie-Line Abou Chacra Vernet

Nathalie Sordello Wagner

Khaled Benkali

Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.

Treatment of papulopustular rosacea with ivermectin

Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.

Treatment of inflammatory lesions of rosacea with ivermectin

Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).

Combination/association of adapalene and benzoyl peroxide for treating acne lesions

Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.

Combinations of adapalene and benzoyl peroxide for treating acne lesions

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Mougins, France

Michel Poncet