Illumina Corporation

Illumina Cambridge Limited

Moon, John a.

Michel Perbost

Michal Lebl

Kevin L Gunderson

John A Moon

Boyan Boyanov

M Shane Bowen

Cheng-Yao Chen

Jeffrey G Mandell

David Louis Heiner

Ryan M Smith

Jingwei Bai

John M Beierle

Mark J Nibbe

Ryan Christopher Smith

Timothy J Merkel

Steven H Modiano

Steven Modiano

Chad F Derosier

Steve R Burgett

Heng Huang

Vicky V Lam

Nilda Juan

Nicole Lee

Xavier Von Hatten

A method of nucleic acid sequencing. The method can include the steps of (a) providing a polymerase tethered to a solid support charge sensor; (b) providing one or more nucleotides, whereby the presence of the nucleotide can be detected by the charge sensor; and (c) detecting incorporation of the nucleotide into a nascent strand complementary to a template nucleic acid.

Biochemically activated electronic device

Disclosed herein are compositions, methods and systems for the processing of chemical reactions, such as the synthesis of polymers.

Methods and compositions for processing chemical reactions

A plurality of isolated microvessels including a plurality of encoded microvessels each having a microbody and a reservoir core. The microbody is configured to separate a biological or chemical substance in the reservoir core from an ambient environment surrounding the microbody. The microbody includes a transparent material that at least partially surrounds the reservoir core and facilitates detection of an optical characteristic of the substance within the reservoir core. The microbody of each microvessel includes an identifiable code that distinguishes individual microvessels of the plurality of encoded microvessels from each other. The plurality of isolated microvessels also includes a plurality of compartments each configured to separate individual microvessels of the plurality of encoded microvessels from each other.

Microvessels, microparticles, and methods of manufacturing and using the same

A method of reading a plurality of encoded microvessels used in an assay for biological or chemical analysis. The method can include providing a plurality of encoded microvessels. The microvessels can include a respective microbody and a reservoir core configured to hold a substance in the reservoir core. The microbody can include a material that surrounds the reservoir core and facilitates detection of a characteristic of the substance within the reservoir core. Optionally, the material can be transparent so as to facilitate detection of an optical characteristic of a substance within the reservoir core. The microbody can include an identifiable code associated with the substance. The method can also include determining the corresponding codes of the microvessels.

Growing community of inventors

San Diego, CA, United States of America

Michel Perbost