Aventis Pharma S.a.

Aventis Pharmaceuticals Products Inc.

Michel Lavigne

Stephane Mutti

Joel Malpart

Christophe Daubie

Robert Stammler

Patrick Leon

Michel Cheve

Eric Didier

Luc Grondard

Joerg Rieke-Zapp

Benoit J Vanasse

Adam W Sledeski

Jean-Rene Authelin

James J Mencel

St&eacute;phane Mutti

Robert C Liu

Veronique Crocq-Stuerga

Geoffrey A D'Netto

Irina Malejonock

Jean-Paul Casimir

The present invention relates to a novel method for the preparation of azetidine derivatives such as N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-quinol-6-ylmethylsulfonamide and the dihydrochloride thereof and N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.

Product, method and intermediates for the preparation of azetidine derivatives

Novel processes for the preparation of a compound of the thiazolo[3,4,5-de] [4,1]benzothiazepine type and in particular of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de] [4,1]benzothiazepine 6,6-dioxide methanesulfonate and (R,S)-2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de] [4,1]benzothiazepine 6-oxide and its enantiomers and their pharmaceutically acceptable salts.

Process for the manufacture of a product of the thiazolo [3,4,5-de] [4,1]benzothiazepine type

Process for the preparation of combretastatins

Method for preparing aspartylcyclohexyla laninamide

This invention is directed to a process for preparing a pseudotetrapeptide of formula I

Process for the preparation of azacycloalkylakanoyl pseudotetrapeptides

The present invention is directed to 4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1-hydroxy-9-oxo- 19-norcyclopropa(g)tax-11-en-13.alpha.-yl (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate and a process for its preparation.

4,10-.beta.-diacetoxy-

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Michel Lavigne