Adir Et Compagnie

Science Union Et Cie

Adir

Science Union Et Cie, Societe Francaise De Recherche Medicale

Adir, S.a.r.l.

Science Union Et Cie, Societe Francaise De Recherche Medical

Science Union Et Cie, Societe Francaise De Recherche Med.

Adir Et Lie

Michel Laubie

Gilbert Lavielle

Georges Remond

Michel Vincent

Francis Colpaert

Tony Verbeuren

Gilbert Regnier

Charles E Malen

Jean-Claude Poignant

Jean-Jacques Descombes

Roger Canevari

Jean-Michel Lacoste

Pierre Roger

Jacques Duhault

Alex Cordi

Olivier Muller

Alain Dhainaut

Serge Simonet

Thierry Dubuffet

Guillaume De Nanteuil

Mark Millan

Alain Rupin

Patrick Hautefaye

Christine Lila

Monique Desnos

Bernard Portevin

Philippe Gloanec

Jacques DuHault

Francois Roman

Jean-Louis Peglion

Philippe Maillos

Jean-Claude Poignantw

Gilbert Reginier

Compounds of formula (I): ##STR1## in which: X represents --CH.sub.2 --, --(CH.sub.2).sub.2 --, --CH.dbd.CH--, --O--CH.sub.2 --, --S--CH.sub.2 --, --SO--CH.sub.2 -- or --SO.sub.2 --CH.sub.2 --,

Benzospiroalkene compounds

The invention relates to the compounds of formula (I): ##STR1## in which: R.sub.1 denotes hydrogen, acyl, alkoxycarbonyl, benzyloxycarbonyl, phenoxycarbonyl or linear or branched C.sub.1 -C.sub.6 alkyl, substituted or unsubstituted, or R.sub.6 SO.sub.2 -- in which R.sub.6 denotes alkyl, naphthyl, phenyl, benzyl or morpholine,

Peptide compounds derived from boronic acid

Benzospiroalkenes

##STR1## in which: R.sub.1 and R.sub.2, which may be identical or different, represent hydrogen or halogen, alkyl, substituted or unsubstituted phenyl, benzyl, pyridylmethyl or imidazolylmethyl or thiazolylmethyl, pyridyl, imidazolyl or thiazolyl, or alternatively,

1,2,3,4-tetrahydronaphthalene compounds

Compounds of formula (I): ##STR1## wherein: --X represents --CH.sub.2 --, --(CH.sub.2).sub.2 --, --CH.dbd.CH--, --O--CH.sub.2 --, --S--CH.sub.2 --, --SO--CH.sub.2 -- or --SO.sub.2 --CH.sub.2 --,

Benzospiroalkene derivatives

A compound of formula (I): ##STR1## in which: R.sub.1 represents hydrogen or acyl, alkyl, benzyl, alkoxycarbonyl, benzyloxycarbonyl, phenoxycarbonyl, 5-[(dimethyl)amino]naphthylsulfonyl, alkoxycarbonylmethyl or carboxymethyl,

Compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which may be identical or different, represent a linear or branched (C.sub.1 C.sub.6) alkyl radical, a substituted or unsubstituted phenyl radical, a pyridyl radical or a thienyl radical, or, with the carbon atom to which they are attached, a substituted or unsubstituted (C.sub.4 -C.sub.7) cycloalkyl ring, R.sub.3 represents

Alkenecarboxylic acid compounds

Benzospiroalkene heterocyclic compounds

Components of formula (I): ##STR1## in which: R.sub.1 represents optionally substituted phenylsulfonyl, naphthylsulfonyl, quinolyl, or isoquinolyl,

Pyrrolidine compounds which are useful as thromboxane AZ-inhibitors

Compounds of formula (I): ##STR1## in which: R.sub.1 represents:

Pyrrolidine compounds

The invention relates to a compound of formula (I): ##STR1## in which: R.sub.1 represents hydrogen or halogen, alkyl, alkoxy, cyano or aminocarbonyl or any one of the following: ##STR2## in which: m is equal to 1, 2 or 3,

Indole, indazole and benzisoxazole compounds

Compounds of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, m, n, and R are as defined in the Specification. Medicinal products containing the same are useful in the treatment or prevention of thrombotic afflictions due to their thromboxane A.sub.2 receptor antagonistic activity and their thromboxane A.sub.2 synthase inhibitory activity.

Pyrrolidine compounds having thromboxane A.sub.2 receptor antagonistic

The invention relates to compounds of formula I: ##STR1## in which R.sub.1 represents a naphthyl radical, a dihydronaphthyl radical, a tetrahydronaphthyl radical, a quinolyl radical or a 1,4-benzodioxanyl radical, A represents a single bond, a double bond, a methylene radical, a radical of formula z.sub.1 :

Piperidine, tetrahydropyridine and pyrrolidine compounds

Piperidine, Tetrahydropyridine and pyrrolidine compounds

Growing community of inventors

Vaucresson, France

Michel Laubie