Synt : Em

Synt:em S.a.

Michel Kaczorek

Jamal Temsamani

Roger Lahana

Mark Elliott Johnson

Fiona Hamilton Day

Gérard Grassy

Philippe Clair

Abdelaziz Yasri

The invention concerns a pharmaceutical composition for treating and/or preventing cancer comprising at least an anti-cancer agent, characterised in that said anticancer agent is associated in the composition with at least a peptide capable of carrying said agent into the cancer cells and prevent the occurrence of chemoresistance to said agent.

Pharmaceutical composition comprising an anti-cancer and at least a peptide

The invention concerns the use of a linear peptide paired with an active substance for diagnosing or treating a CNS pathology by preparing a medicine capable of crossing the blood brain barrier to be used for diagnosis or treatment of a pathology localized in the CNS.

Peptides carrying substances across the blood brain barrier

The invention relates to conjugates of an antigen coupled to a linear derivative of a &#x3b2;-stranded antibiotic peptide, which are useful for immunogenic agents to enhance a CTL response. Two groups of preferred peptides are derived from the antibiotics protegrin and tachyplesin.

Use of peptide vectors to improve the immune response to antigens

The present invention is concerned with a computer-aided method for the provision, identification and description of molecules exhibiting a desired behaviour, more particularly in the pharmaceutical sector, employing a molecular modelling step, a combinatorial library building step and a step of selecting potentially useful molecules, said method including a step whereby the candidate molecules are filtered using a dynamic filter representing constraints of conformational variations which the molecules must satisfy in order to exhibit said activity.

COMPUTER-AIDED METHOD FOR THE PROVISION, IDENTIFICATION AND DESCRIPTION OF MOLECULES CAPABLE OF EXHIBITING A DESIRED BEHAVIOR, MORE PARTICULARLY IN THE PHARMACEUTICAL SECTOR, AND MOLECULES OBTAINED BY SAID METHOD

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Montferrier sur Lez, France

Michel Kaczorek