Centre National De La Recherche Scientifique

Institut Pasteur

Michel Brahic

Chantal Combredet

Valérie Labrousse-Najburg

Frédéric Tangy

Fréderic Tangy

Valerie Labrousse-Najburg

Valérie Labrousse Najburg

The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also concerns the preparation of immunogenic compositions using said cDNA.

Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions

The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also contains the preparation of immunogenic compositions using said cDNA.

The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain, for example, the Schwarz strain. It also concerns the preparation of infectious recombinant viruses and immunogenic compositions using the cDNA.

Growing community of inventors

Saint Germain-en-Laye, France

Michel Brahic