Merial Limited

Virogenetics Corporation

Rhone Merieux

Rhone Merieux, Societe Anonyme

Michel Albert Riviere

Jean-Christophe Francis Audonnet

Annabelle Bouchardon

Philippe Guy Baudu

Enzo Paoletti

James Tartaglia

Michel Joseph Bublot

William I Cox

Jill Taylor

Steven E Pincus

Russell Robert Gettig

Charles De Taisne

Keith J Limbach

Raphael Jean Darteil

Marion E Perkus

Gerard P Johnson

Elizabeth K Norton

Eliane Louise Laplace

Carole Veronique Duinat

Louis Joseph Ross

Jean-Christophe Francedillais Audonnet

Vladimir Zelnik

Disclosed are plasmids that contain and express in vivo in a feline host cell nucleic acid molecules. The plasmid can include nucleic molecule(s) having sequence(s) encoding infectious peritonitis virus M; feline immunodeficiency virus env, or gag, or pro, or gag and pro, or env and gag and pro; rabies G; or feline leukemia virus env and/or gag. Compositions containing such plasmids, methods of use employing such plasmids, and kits involving such plasmids, are also disclosed.

Feline polynucleotide vaccine formula

Disclosed is an immunological or vaccine composition that includes at least one plasmid that contains and expresses in vivo in host canine cells a nucleic acid molecule that encodes an antigen of a canine pathogen, such as rabies G. The plasmid can include more that one nucleic acid molecule such that the plasmid can express more than one antigen. Also disclosed are methods for using and kits employing such compositions.

Polynucleotide vaccine formula against canine pathologies, in particular respiratory and digestive pathologies

Disclosed and claimed are compositions for inducing in a bovine host an immunological response against bovine respiratory syncytial virus or bovine viral diarrhea virus containing at least one plasmid that contains and expresses in vivo in a bovine host cell nucleic acid molecule(s) having sequence(s) encoding bovine respiratory syncytial virus F protein, or G protein, or F and G proteins; or, at least one plasmid that contains and expresses in vivo in a bovine host cell nucleic acid molecule(s) having sequence(s) encoding bovine viral diarrhea virus E2 protein, or C, E1 and E2 proteins, or E1 and E2 proteins. Methods and kits employing such compositions are also disclosed.

Polynucleotide vaccine formula in particular against bovine respiratory pathology

Disclosed is an immunological or vaccine composition that includes at least one plasmid that contains and expresses in vivo in host canine cells a nucleic acid molecule that encodes an antigen of a canine pathogen, such as rabies G. The plasmid can include more than one nucleic acid molecule such that the plasmid can express more than one antigen. Also disclosed are methods for using and kits employing such compositions.

Disclosed and claimed is: an immunogenic or vaccine composition for inducing in an avian host an immunological response against avian pathologies containing at least one plasmid that contains and expresses in vivo in an avian host cell nucleic acid molecule(s) having sequence(s) encoding antigen(s) of the avian pathogen(s); and, methods for using and kits employing such compositions.

Polynucleotide vaccine formula against porcine reproductive and respiratory pathologies

Disclosed and claimed is: an immunogenic or vaccine composition for inducing in an equine host an immunological response against equine pathologies containing at least one plasmid that contains and expresses in vivo in an equine host cell nucleic acid molecule(s) having sequence(s) encoding antigen(s) of the equine pathogen(s); and, methods for using and kits employing such compositions.

Polynucleotide vaccine formulation against pathologies of the horse

An avian plasmid vaccine contains a plasmid, and a pharmaceutically acceptable carrier. The plasmid contains and expresses in vivo in an avian host cell a nucleic acid molecule having a sequence encoding the Newcastle disease virus HN protein. The plasmid can further contain and express in vivo in an avian host cell a nucleic acid molecule having a sequence encoding the Newcastle disease virus F protein.

Avian polynucleotide vaccine formula

Disclosed is an immunological composition that includes at least two plasmids; each plasmid contains and expresses in vivo in host canine cells a nucleic acid molecule that encodes an antigen of a canine pathogen. The plasmids can include more than one nucleic acid molecule such that the plasmids can express more than one antigen. The composition can include a first plasmid that contains and expresses a nucleic acid molecule encoding canine parvovirus VP2 and a second plasmid that contain(s) and express(es) nucleic acid molecule(s) encoding canine distemper HA and/or F.

Polynucleotide vaccine formula against canine pathologies

The avian vaccine formula comprises at least three polynucleotide vaccine valencies each comprising a plasmid integrating, so as to express it in vivo in the host cells, a gene with one avian pathogen valency, these valencies being selected from the group consisting of Marek's disease virus, Newcastle disease virus, infectious bursal disease virus, infectious bronchitis virus, infectious anaemia virus, the plasmids comprising, for each valency, one or more of the genes selected from the group consisting of gB and gD for the Marek's disease virus, HN and F for the Newcastle disease virus, VP2 for the infectious bursal disease virus, S, M and N for the infectious bronchitis virus, C&plus;NS1 for the infectious anaemia virus.

Avian polynucleotide formula

The present invention relates to a vaccine formula allowing in particular the vaccination of pigs against reproductive and respiratory pathologies. It also relates to a corresponding method of vaccination.

Polynucleotide formula against porcine reproductive and respiratory pathologies

Disclosed and claimed is: an immunogenic or vaccine composition for inducing in an equine host an immunological response against equine rhinopneumonitis virus (EHV) containing at least one plasmid that contains and expresses in vivo in an equine host cell nucleic acid molecule(s) having sequence(s) encoding EHV gB, gD, or gB and gD; an immunogenic or vaccine composition for inducing in an equine host immunological response against encephalomyelitis virus containing at least one plasmid that contains and expresses in vivo in an equine host cell nucleic acid molecule(s) having sequence(s) encoding encephalomyelitis virus C, E2, or C and E2 proteins; and, methods for using and kits employing such compositions.

Polynucleotide formulation against pathologies of the horse

The living recombinant avian vaccine comprises, as a vector, an ILTV virus comprising and expressing at least one heterologous nucleotide sequence, this nucleotide sequence being inserted in the insertion locus defined between the nucleotides 1624 and 3606 at the SEQ ID NO: 5. The vaccine may in particular comprise a sequence coding for an antigen of an avian pathogenic agent selected among the group consisting of the Newcastle disease virus (NDV), the infections bursal virus (IBDV), the Marek disease virus (MDV), the infectious bronchitis virus (IBV), the chicken anaemia virus (CAV), thee chicken pneumovirosis virus, preferably under the control of a strong eukariotic promoter. A multivalent vaccine formula is also disclosed.

Avian recombinant live vaccine using, as vector, the avian infectious

The recombinant live vaccine comprises, as vector, a feline herpesvirus comprising and expressing at least one nucleotide sequence encoding a polypeptide, this sequence being inserted into the ORF5 and/or ORF2 sites. Polyvalent vaccine formula and feline herpesvirus DNA fragments.

Growing community of inventors

Ecully, France

Michel Albert Riviere