Paieon Inc.

Other

Michael Zarkh

Moshe Klaiman

Rafael Shmeul Brada

Amir Blumenfeld

Rami Evron

Tsuriel Assis

Klaiman Moshe

Rafael Brada

Method and apparatus for detecting and analyzing heart mechanical activity at a region of interest of a patient's heart are provided. The method comprises acquiring a time sequence of 2-dimensional X-ray images of a region of interest over at least part of a cardiac cycle; detecting coronary vessels in the X-ray images; tracking the coronary vessels through the sequence of images to identify movements of the coronary vessels; and analyzing the movements of the coronary vessels to quantify at least one parameter characterizing heart wall motion in the region of interest.

Method and system for detecting and analyzing heart mechanics

A method for determining by an x-ray projection a position of a target radiopaque marker disposed on a catheter in a subject's body, comprising assigning a landmark in the body as a reference point compensated for periodic movements of the body, determining an auxiliary location relative to the reference point using at least one additional radiopaque marker disposed on the catheter and based on the auxiliary location determining the position of the target radiopaque marker with respect to the reference point.

Apparatus and method for locating a device tip within a volume

An apparatus and method for placing a device in a body area of a patient, by: tracking the device over a 3-dimensional model of the body area; activating the device at different locations in the body area; measuring the response signal or parameter caused by the activation; storing the locations as well as the response signals; choosing an optimal location for the device base in the stored response signals and navigating the device to the optimal location.

Method and apparatus for positioning a biventrivular pacemaker lead and electrode

A method and apparatus for navigating a therapeutic device to a location in a moving organ. A feature is identified in one reference image, such as a calcified spot. Then the target location for the device is determined. If the feature and the target location are not shown on the same frame, registration is performed, and the geometric relation between the feature and the target location is determined. On the positioning stage, the feature is identified in a positioning image, then the target location is indicated on the image. The user then manipulates the device, also visible on the positioning image to the target location. If the feature is not identified automatically in the positioning image, the target location is assumed at the current location, and the feature is marked, which assists the user in identifying the real location of the feature, and manipulating the device to the target location.

Method and apparatus for navigating a therapeutic device to a location

An apparatus and method for detecting, tracking and registering a device () within a tubular organ () of a subject. The devices include guide wire () tip or therapeutic devices, and the detection and tracking uses fluoroscopic images taken prior to or during a catheterization operation. The devices are fused with images or projections of models depicting tile tubular organs. Tile method and apparatus are used for treating chronic total occlusion or near total occlusion situations, by navigating a driller along the tubular organ () proximally to the occlusion point, in areas which are-not viewable in an angiogram, and optionally enabling the penetration of the occlusion in a preferred area.

Method and apparatus for guiding a device in a totally occluded or partly occluded tubular organ

An apparatus and method for detecting, tracking and registering a device within a tubular organ of a subject. The devices include guide wire tip or therapeutic devices, and the detection and tracking uses fluoroscopic images taken prior to or during a catheterization operation. The devices are fused with images or projections of models depicting the tubular organs.

Method and apparatus for positioning a device in a tubular organ

Embodiments of the present invention include methods and systems for three-dimensional reconstruction of a tubular organ (for example, coronary artery) using a plurality of two-dimensional images. Some of the embodiments may include displaying a first image of a vascular network, receiving input for identifying on the first image a vessel of interest, tracing the edges of the vessel of interest including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel, displaying at least a second image of the vascular network, receiving input for identifying on the second image the vessel of interest, tracing the edges of the vessel of interest in the second image, including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel in the second image, determining a three dimensional reconstruction of the vessel of interest and determining fused area (cross-section) measurements along the vessel and computing and presenting quantitative measurements, including, but not limited to, true length, percent narrowing (diameter and area), and the like.

System and method for three-dimensional reconstruction of a tubular organ

A method and system for quantifying a cyclic motion within a series of images depicting a moving object subject to composite motion containing a cyclic component and a non-cyclic component of lower frequency than the cyclic component. Composite motion is computed as well as the non-cyclic component as the integral of motion over a motion cycle. The non-cyclic component is subtracted from the composite motion so as to obtain the cyclic component

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Giv′at-Shmuel, Israel

Michael Zarkh