Wyeth

Pfizer Corporation

Wyeth Holdings Corporation

Michael William Winkley

Panolil C Raveendranath

Christoph Martin Dehnhardt

Anthony Francis Hadfield

Ronald Stanley Michalak

Mousumi Ghosh

Mahmut Levent

Charles Guinosso

Frederick J Vyverberg

Ara R Boyajian

Michel Cantin

Alan Stockton

Syed Muzafar Shah

Karen Sutherland

Aranapakam Mudumbai Venkatesan

Ivo L Jirkovsky

Tarek Suhayl Mansour

Beat Theodor Weber

Joseph Zeldis

Anita Wai-Yin Chan

Aeri Park

Michael Z Kagan

Gulnaz Khafizova

Henry Strong

Antonia Nikitenko

Kenneth Alfred Martin Kremer

James Andrew Provost

Brenton William Russell

Rex Alwyn Shipplett

Rex A Shipplett

Karen Wiggins Sutherland

Ronald S Michalak

Christoph Dehnhardt

The present invention provides a compound of formula 1: wherein Ris CF, Ris H' Ris H.

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The present invention provides method for making a compound of formula 1: comprising the steps of reacting compounds of formulas 2 and 3: to produce a compound of formula 4: wherein R, R, R, Rand Rare defined as described herein. The compound of formula 4 is then converted to the compound of formula 1. The invention further comprises compounds of formulas 3 and 4 and methods for making compounds of formulas 3 and 4.

There is provided a process for the preparation of bicyclicheteroaryl carboxaldehydes having the structural Formula I where X and Y are defined in the specification  The bicyclic heteroaryl carboxaldehydes are useful as intermediates in the preparation of &#x3b2;-lactamase inhibitors.

Process for synthesizing beta-lactamase inhibitor intermediates

A novel salt of O-desmethylvenlafaxine, O-desmethylvenlafaxine formate, is provided. Pharmaceutical compositions, dosage forms and methods of use are also provided.

Formate salt of O-desmethyl-venlafaxine

A novel salt of O-desmethyl venlafaxine is provided, O-desmethylvenlafaxine succinate. Pharmaceutical compositions, dosage forms and methods of use are also provided.

Succinate salt of O-desmethyl-venlafaxine

B-ring estratriene diols

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Campbell Hall, NY, United States of America

Michael William Winkley