The Hartz Mountain Corporation

Summit Vetpharm, LLC

Michael William Lytwyn

Ian Cottrell

Albert Ahn

Pierre R Joseph

Christine M Monro

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1-{(tetrahydro-3-furanyl)methyl}-2-nitro-3-methylguanidine(dinotefuran), an aldulticide that will kill adult fleas combined with methoprene.

High concentration dinotefuran formulations containing methoprene

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1-{(tetrahydro-3-furanyl)methyl}-2-nitro-3-methylguanidine (dinotefuran), an aldulticide that will kill adult fleas combined with pyriproxyfen.

High concentration topical insecticide containing pyriproxyfen

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1-&lcub;(tetrahydro-3-furanyl)methyl&rcub;-2-nitro-3-methylguanidine (dinotefuran), an aldulticide that will kill adult fleas, dissolved in a solvent such as ethanol and/or DPM.

Topical insecticide

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1-&lcub;(tetrahydro-3-furanyl)methyl&rcub;-2-nitro-3-methylguanidine (dinotefuran), an aldulticide that will kill adult fleas, dissolved in phenyl methanol or ethanol and ethyl lactate.

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East Hanover, NJ, United States of America

Michael William Lytwyn