The Procter Gamble Company

Michael Wiard Scherz

Randall Stryker Matthews

John M Janusz

Stanislaw Pikul

Laurence Ichih Wu

A compound having the structure: ##STR1## wherein (a) W is --C(X')--NRR' or --NR--C(X')R';

Dihydorbenzofuran and related compounds useful as anti-inflammatory

A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3;

Dihydrobenzofuran and related compounds useful as anti-inflammatory

A compound having the structure: ##STR1## wherein (a) X is oxygen or sulfur;

Dihydrobenzothiophene compounds useful as anti-inflammatory agents

A compound having the structure: ##STR1## wherein (a) X is oxygen or sulfur; (b) each Y is independently hydrogen or unsubstituted straight, branched or cyclic alkanyl having from 1 to about 3 carbon atoms,. or the two Y's are bonded to form an alkanyl ring having from 3 to about 7 carbon atoms; (c) Z is hydrogen or unsubstituted branched or cyclic alkyl, or unsubstituted or alkanyl-substituted phenyl, having from 3 to about 10 atoms other than hydrogen; (d) W is straight, branched or cyclic alkyl or aryl, unsubstituted or substituted, saturated or mono- or di-unsaturated with double bonds except that no terminal carbon atom of W is part of a double bond; W having from 1 to about 15 atoms other than hydrogen; pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.

The subject invention relates to compounds having the structure: ##STR1## wherein a) each R is independently alkyl having from 1 to about 7 carbon atoms;

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West Chester, OH, United States of America

Michael Wiard Scherz