Schering Corporation

Michael W Leach

Gregory A Reichard

Jonathan A Pachter

Elmer J Mirro

Dineshwar Sinha

Mark R Berardi

Mark E Cartwright

Use of an antagonist selected from the group consisting of: (a) antagonists of neurokinin-1 (NK ), neurokinin-2 (NK ) and neurokinin-3 (NK ) receptors, (b) antagonists of NK and NK receptors, (c) antagonists of NK and NK receptors, (d) antagonists of NK and NK receptors, (e) antagonists of NK receptors, and (f) antagonists of NK to treat symptoms and disorders associated with a production and/or secretion of androgen. One aspect of the invention relates to the use of antagonists to suppress production/secretion of androgens in mammals suffering from an androgen-dependent disease, such as benign prostatic hyperplasia and prostatic carcinoma.

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Shrewsbury, MA, United States of America

Michael W Leach