Avant Medical Corporation

Avant Drug Delivery Systems, Inc.

Michael W Burk

John B Slate

Corey Michael Magers

Richard J Koerner

Lanny A Gorton

Andrew C Barnes

Corey M Magers

An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.

System and method for an injection using a syringe needle

An autoinjector system for injecting a fluid medicament into a patient includes a re-usable autoinjector, and a disposable cassette loaded with a hypodermic syringe pre-filled with a fluid medicament. The autoinjector includes a first motor for injecting a needle of the hypodermic syringe into the patient and a second motor for expelling the fluid medicament from the syringe.

Autoinjector system

A system for injecting a fluid medicament into a patient includes a drive mechanism, and a cassette loaded with a pre-filled hypodermic syringe. When the cassette is loaded, the syringe is held firmly inside and the cassette can be selectively engaged with the drive mechanism. The drive mechanism has two motors. A first motor initially moves the hypodermic syringe from a position inside the cassette where its needle is concealed, to a position where the needle extends from the cassette for insertion into a patient for an injection. With the needle inserted, a second motor pushes the syringe stopper to expel a fluid medicament from the syringe. After an injection, the first motor withdraws the syringe back into concealment inside the cassette, to again firmly hold the syringe on the cassette. The cassette and syringe, in combination, can then be removed from the drive mechanism and discarded.

Cassette for a hidden injection needle

A system and method to automatically initiate an injection procedure of a medicament into a patient. In the system, a delivery assembly includes an injector for infusing the medicament into the patient. Further, the system includes a monitor for detecting a parameter characteristic of the procedure, for instance, a pressure indicative of a partial vacuum between the injector and the injection site, a pressure exerted by the patient against the delivery assembly, a conductance, a capacitance, or an optical blood reading. Also, the system includes a timer for determining compliance of the parameter within a predetermined range during a first time interval. In response to the timer, an actuator initiates the injection procedure at the expiration of the first time interval. Further, the actuator may stop the injection procedure if the parameter is outside the predetermined range during a second time interval.

Device and method for the automatic initiation of an injection

A device and two-step sequential method for providing medication for injection and infusion by a jet injector includes a cassette which connects an injector system to a reservoir. The cassette forms a fluid pathway at an interface of a cassette lower body and a cassette upper body. The cassette also forms an impulse chamber with a nozzle leading therefrom. The fluid pathway interconnects the reservoir with the impulse chamber. The medication flows from the reservoir along the fluid pathway and into the impulse chamber. Force from an impulse generator drives the fluid medicament from the impulse chamber through the nozzle, out an orifice in a tip of the nozzle, and into the skin of a patient. To prevent the pressure waves generated by the jet injector from damaging a glass reservoir, the fluid pathway is formed with pressure attenuators.

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San Marcos, CA, United States of America

Michael W Burk