Biotronik Crm Patent Ag

Michael V Orlov

Dirk Muessig

Christopher S De Voir

Jie Lian

Dirk Müssig

Sharon Lefkov

Sharon Levkov

Pacemaker-initiated atrial fibrillation during competitive atrial pacing is a common arrhythmia with potentially serious consequences The novel pacing method proposes a novel way to automatically detect and diagnose competitive atrial pacing, and to deliver an intervention via a pacing stimulus in the atrium simultaneously with delivering a pacing stimulus in the ventricle, and doing this after a longer waiting period. By doing this, potentially hazardous scenarios causing atrial fibrillation in competitive atrial pacing are avoided, while the rhythm regularity and the synchrony between the upper and lower chambers of the heart are maintained. At the same time, the vicious cycle of retrograde conduction from the ventricle to the atrium—the culprit of the problem—is terminated and not allowed to reoccur for several subsequent cardiac cycles, thereby preventing the extended propagation of repetitive non-reentrant ventriculo-atrial synchrony.

Methods for operating a dual-chamber pacemaker to avoid triggering atrial fibrillation and perpetuation of repetitive ventriculo-atrial synchrony

The invention refers to a monitoring device for monitoring and analyzing physiological signals. The monitoring device comprises a transthoracic impedance measurement unit and an evaluation unit connected to the transthoracic impedance measurement unit. The transthoracic impedance measurement unit is adapted to conduct a transthoracic impedance measurement and to generate a transthoracic impedance signal representing a measured transthoracic impedance at consecutive points in time. The evaluation unit being configured to process the transthoracic impedance signal received from the transthoracic impedance measurement unit and to thus generate a respiration signal and to generate therefrom an evaluation signal reflecting at least a diurnal pattern of the respiration rate.

Night respiration rate for heart failure monitoring

Heart monitoring apparatus with sensing stage connectable to intracardiac electrode picking up electric potentials and adapted to process electric signals representing a time course of said potentials, a mechanical action detection stage adapted to generate a geometry signal having a time course reflecting heart chamber's geometry change, an evaluation unit connected to sensing stage and impedance measuring stage and adapted to determine a first and second fiducial point in the time course of said potentials and geometry signal, respectively, both fiducial points belonging to same heart cycle, and to determine a measured time delay between said fiducial points. Evaluation unit adapted to repeat said determined time delay to determine plurality of measured time delays and variance thereof or divergence of the statistical properties of cycle times based on said time course of said electric potentials versus cycle times based on said time course reflecting a change of a heart chamber's geometry.

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Brookline, MA, United States of America

Michael V Orlov