Scimed Life Systems, Inc.

Cryocath Technologies Inc.

Michael Urick

Daniel Nahon

James G Hansen

Leonilda Capuano

Willard W Hennemann

Patrick Chauvet

Scott Andrus

A method is disclosed for treating an aneurysm by cooling a target tissue region of the aneurysm to a temperature below temperature for a preselected time period. The method entails thickening, strengthening, or increasing the density of a blood vessel wall by cooling the blood vessel wall with a cryogenically cooled device. In particular, a device having a heat conductive cooling chamber is disposed proximate to the aneurysm site; and a cryogenic fluid coolant is directed to flow inside the chamber to create endothermic cooling relative to the aneurysm. The method also promotes the growth of collagen and elastin in vascular tissue. Tissue cooling temperatures range from &plus;20 to &minus;20 degrees Celsius. The duration of treatment by application of cooling ranges from 15 seconds to up to 20 minutes or more. The method includes treating the aneurysm both from inside and outside the blood vessel wall forming the aneurysm.

Method and device for treatment of aneurysms

An inflation device such as a syringe is preloaded with gas (other than air) for inflation of balloon catheters. The syringe is lined with, or is packaged within, a low gas-permeability membrane to keep the stored gas from becoming contaminated with air. The physician using the syringe is able to determine whether air has infiltrated the syringe and contaminated the gas stored in the syringe.

Preloaded gas inflation device for balloon catheter

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Beaconsfield, Canada

Michael Urick