Integrated Genetic Devices Ltd.

Yeda Research and Develpment & Co. Ltd

Tel Aviv University

Therapix Biosciences Ltd.

Michael Tal

Yoram Liran

Timothy David Jones

Sarit Samira

Nurit Rachamim

Ronald Ellis

Francis Joseph Carr

Beka Solomon

Israel Pecht

Marcelo D Guthmann

Polina Rabinovich-Toidman

Meital Sooliman

Zvi Koren

Rom E Eliaz

Shahar Dotan

Idan Rakover

Joshua Livneh

Humanized monoclonal antibodies (mAbs) or fragments thereof, to human Cluster of Differentiation 3 (CD3), which confer improved immune stimulation and stability, are disclosed. Pharmaceutical compositions comprising said mAbs and methods of treatment and optionally also prevention of diseases and disorders, such as autoimmune disorders, infectious diseases, and transplant rejection, that are susceptible to amelioration by binding to CD3, are also disclosed.

Humanized antibodies to cluster of differentiation 3 (CD3)

Novel antibodies, methods and compositions for treatment of a disease which is susceptible to amelioration by the blocking of APP cleavage.

Methods and compositions with immune therapy for treatment of dementia

A method and apparatus for effecting rapid thermal cycling of samples, by producing a high-velocity air flow through a closed loop flow path, and energizing an electrical heater within the closed loop flow path to heat the air flowing therethrough to a desired temperature. A sample holder is introduced into the closed loop flow path for exposing the sample holder to the high-velocity heated air flowing therethrough for rapidly heating the sample. The sample is rapidly cooled to a desired temperature by de-energizing the electrical heater, and opening an air outlet from the closed loop flow path, while continuing to produce the high-velocity air flow therethrough.

Method and apparatus for effecting rapid thermal cycling of samples in microtiter plate size

An electrophoretic system for real time analysis of a plurality of samples each containing at least one biopolymer is disclosed. The system includes (a) a holder for holding a plurality of removable gel cassettes, the holder supporting a plurality of electrode pairs electrically connectable to an external power source; (b) the plurality of removable gel cassettes each having an open top end and a bottom end and being designed for containing a gel slab therein, wherein each pair of the plurality of electrode pairs serves for creating a voltage gradient in a single gel slab, such that electrophoretic separation of the at least one biopolymer of each of the plurality of samples is effectable thereby; (c) a plurality of detector assemblies each including a plurality of detection units, each of the plurality of detector assemblies being intimately positionable at a region of one of the plurality of removable gel cassettes corresponding to a portion of the gel slab, each of the plurality of detector assemblies being for collecting information pertaining to at least one property of at least one biopolymer from the portion of the gel slab, whereas each of the plurality of detection units of a single detector assembly of the plurality of detector assemblies serves for collecting information pertaining to at least one property of at least one biopolymer in a subregion of the portion of the gel slab.

Electrophoretic system for real time detection of multiple electrophoresed biopolymers

An apparatus for controlling the temperature of at least one liquid reaction mixture, the apparatus including (a) at least one reaction vessel having open proximal and distal ends, the at least one reaction vessel including a gas permeable, liquid retaining, barrier positioned at a proximal portion thereof; (b) a pump being in fluid communication with the proximal end of the at least one reaction vessel through the barrier, for generating negative or positive pressure within the at least one reaction vessel, for translocating the at least one liquid reaction mixture through the distal end into and out of the at least one reaction vessel; and (c) a temperature controller being in thermal communication with the at least one reaction vessel for controlling the temperature of the at least one liquid reaction mixture when maintained within the at least one reaction vessel.

Apparatus, system and method for automated execution and analysis of biological and chemical reactions

DNA molecule encoding a mast cell function-associated antigen (MAFA)

Growing community of inventors

Kfar Bilu, Israel

Michael Tal