Medi-physics, Inc.

General Electric Company

Michael T Schneider

Kevin M Helle

Jay Christopher Reed

Robert F Chisholm

A mixing device including a container defining a container cavity, the container including a bottom wall supporting a hollow shaft, the shaft supporting an impeller thereon such that the impeller is free to rotate about the shaft, the impeller including a central passageway therethrough for receiving the shaft, the container further including an elongated evacuation tube having a first end positioned within the passageway of the shaft and an opposed second end extending to a port of the container. Methods of using the mixing device to provide improved cell culture.

Impeller bottle with an elongated evacuation tube

A dual-filter dual-integrity test conduit assembly allows for in-situ testing of both filters with separate, duplicate systems for membrane integrity so that if the first tester filter fails, the second filter may be tested with a different, but identical method with its own gauges and nitrogen supply so as to further isolate malfunctions of the filter integrity test equipment as a cause for erroneous batch failures.

Dual-filter dual-integrity test assembly

A fluid sampling system for sampling the contents of a container of fluid includes an elongate hollow sampling conduit extending between a first end for withdrawing the fluid from the container and a second end for returning the fluid to the container, pump means for circulating the fluid between the container and the sampling conduit, a sample probe having a tip extending into the sampling conduit so as to contact the fluid within the sampling conduit, and a controller unit for controlling flow of the fluid within the sampling conduit and monitoring the properties of interest of the fluid within the sampling conduit via signals received from the sample probe. The present invention also provides an in-line pH probe.

Fluid sampling system with an in-line probe

The present invention provides a radiation-shielding container for a radiopharmaceutical that may be magnetically picked and placed, assembled and dis-assembled.

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Crystal Lake, IL, United States of America

Michael T Schneider