Praxis, LLC

Adaptilens, LLC

Mast Biosurgery Ag

Michael T Milbocker

Christopher J Calhoun

Liane Clamen

Paul Glazer

Lukas Bluecher

A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states. The preferred bi-phasic medium of the device is comprised of a solid three dimensional polymeric network suspended in a liquid aqueous phase and bonded to a capsular interface. The polymeric network provides shape to the capsular interface, optical power, and a physiologic response to the suspensory ligament. The three dimensional network of the bi-phasic medium mimics the stacked fiber configuration and elasticity of a natural lens. An alternative embodiment utilizing a single phase medium is also disclosed with associated structural features provided in the capsular interface.

Injectable physiologically adaptive intraocular lenses (IOL's)

The present invention relates to a hydrated, biocompatible tissue-augmentation compound and its methodology for implantation into mammalian tissue. The tissue-augmentation compound is comprised of: living tissue, body derived fluids, at least one NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate, and oxyethylene-based diols or polyols comprised essentially all of hydroxyl groups capped with polyisocyanate

In situ bulking device

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Holliston, MA, United States of America

Michael T Milbocker