Etex Corporation

Life Science Enterprises, Inc.

Zimmer Knee Creations, Inc.

Michael Strunk

Aron D Rosenberg

Aliassghar N Tofighi

Tak Lung Chang

Laurent D Gillès De Pélichy

Shrikar Bondre

Bradford J Coale

Greg Stebbins

Imants Liepins

Siddhesh Angle

Various embodiments disclosed relate to curable calcium phosphate compositions for use with porous structures and methods of using the same. In various embodiments, the present invention provides a curable calcium phosphate composition or a cured product thereof, with the curable calcium phosphate composition including calcium phosphate and a perfusion modifier. In various embodiments, the present invention provides an apparatus comprising a porous structure at least partially in contact with the curable calcium phosphate composition or a cured product thereof. The porous structure can include a porous substrate including a plurality of ligaments that define pores of the porous substrate, and a biocompatible metal coating on the plurality of ligaments of the porous substrate.

Curable calcium phosphate compositions for use with porous structures and methods of using the same

Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.

Minimally invasive treatment of vertebra (MITV) using a calcium phosphate combination bone cement

Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.

Porous calcium phosphate bone material

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Woburn, MA, United States of America

Michael Strunk