Bionaut Labs Ltd.

Shpigelmacher, Michael

Michael Shpigelmacher

Alex Kiselyov

Alexander Sromin

Nadav Cohen

Eli Van Cleve

Amir Geron

Florent Cros

Eran Oren

Amitay Peleg

Suehyun Cho

Hovhannes Sargsyan

John Caputo

Dennis Seely

Leslie Field

Mateusz Bryning

Phillip Barth

Olin Palmer

A carrier device and methods of use are described. The device and methods are directed toward implanting in biological tissue and for releasing a medical payload or functional material in biological tissue according to a remote magnetic trigger. The carrier device has a cavity with an opening through an external surface of the device. The carrier device includes at least one moveable, magnetic element sensitive to a magnetic field gradient. When a magnetic field gradient, rotating magnetic field, or uniform magnetic field, or a combination of thereof is applied to the tissue, the moveable magnetic element provides release of the medical payload or functional material through the cavity opening. In some embodiments, payload release can be started, stopped, and restarted at a later time or place. In addition to payload release, devices of this invention are equipped with a propelling element, the propelling element is responsive to external stimuli that enables propulsion and navigation of the device.

Magnetomechanic triggering of payload release from miniaturized devices

A platform and methods of use, for providing active, pre-determined, fully controlled, precise delivery of nano- or micro-particles in biological tissue. The platform comprises the following modules: (A) one or more nano- or micro-particles comprising embedded logic and various MEM components; (B) a delivery and retraction module, configured to deliver and retract the particles; (C) an external signal generator; (D) an imaging module, configured to monitor said particles; and (E) an integration module configured to receive inputs from other modules and provide output control commands to other modules. The modules are configured to interact/communicate with each other and are internally controlled, externally controlled or both.

Methods and systems to control particles and implantable devices

Apparatus and systems for providing magnetic fields for controlling micro-devices implanted in a patient body, organ, or tissue. Novel coil configurations are disclosed which provide magnetic fields of adequate strength and directional characteristics over a large operational region with minimal weight and power dissipation, while providing ease of access to the focus regions. Also provided are micro-devices in various size regimes which can be controlled both in position as well as in function (such as release of therapeutic materials), and which are capable of both energy and data transfer with the magnetic field control system.

Hybrid electromagnetic device for remote control of micro-nano scale robots, medical tools and implantable devices

This invention relates to apparatus for creating a magnetic field to propel a magnetic device within a diverse media including biological matrices, tissues, organs, animals and humans. In one embodiment, a cylindrical dual Halbach array provides a uniform magnetic field with a settable field direction. Another embodiment provides support and orientation apparatus for a controlled-gradient conical magnet to achieve a full 4π steradian solid angle coverage around the specimen.

Magnetic propulsion system for magnetic devices

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Los Angeles, CA, United States of America

Michael Shpigelmacher