Synecor LLC

Peach State Labs, Inc.

Boston Scientific Scimed, Inc.

Stryker Corporation

Barosense, Inc.

Interventional Autonomics Corporation

Medtronic Ave, Inc.

Stryker Nv Operations Limited

Massachusetts Institute of Technology

Stryker European Holdings I LLC

Transenterix, Inc.

Other

The Brigham and Women's Hospital, Inc.

Transenterix Surgical, Inc.

Minimally Invasive Surgical Access Limited

Michael Scott Williams

Richard Glenn

Richard S Stack

William L Athas

Kevin D Holbrook

Jeffrey A Smith

Daniel Wayne Fifer

Joseph Desimone

Ralph R Sargent

Geoffrey Orth

Terrance J Ransbury

Thomas H Moss, Iii

John P Lunsford

Michael Grigat

Robert Samuel Langer

Fred E Silverstein

Lynn H Elliott

Nathan Every

Clifford Teoh

Dan Balbierz

Colleen Stack N'diaye

Joseph M Desimone

Richard O Murphy

Kamal Ramzipoor

Yadong Wang

Scott Anthony McGill

R Richard Sargent

Russell B Ford

Richard A Glenn

Daniel J Balbierz

Carlo Giovanni Traverso

Hancun Chen

Like Que

Trevor Moody

Alex G Abramson

Lantao Guo

Ann Huang

Jimmy D Dao

Justin Vo

Tra Huong Ngo

Stella Chu

Elena Oo

Christina Ma

Aurora Pryor

Robert S Jackson

Thomas N Sargent

James M Anderson

Derek C Sutermeister

Benjamin Y Arcand

Jay T Rassat

Andrew Huffmaster

Matthew J Birdsall

Robert D Lashinski

Gregory Edwin Mirigian

Ester Caffarel Salvador

Jeffrey R Alender

Jacob Wainer

Kirsten Carroll

Charles Daly

John E Nolting

William S Henry

Hanh H Duong

Robert S Langer

Colleen Stack

Samuel L Shull

Jansuz Kowalik

Jason Siu Wei Li

Jacob Coffey

Hughie Devaney

Billy Lee Hullender

Christoph Winfried Johannes Steiger

Steve Allen

Miguel Jimenez

Nathan Jarnagin

Robert Andrus

Josh Land

Geoffrey A Orth

Iii Moss Thomas Hudson

Ralph Richard Sargent

Trevor J Moody

Richard R Sargent

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).

Self-righting systems, methods, and related components

A platform technology has been designed to provide a means for controlled delivery of single or multiple doses of therapeutic, prophylactic, diagnostic or identifying agents to livestock. The delivery system is based on a livestock ear tag that releases therapeutic and/or prophylactic agent when applied to the ear or other desired anatomical target of the animal. The agent to be delivered is encapsulated in or on microneedles and or microparticles and or nanoparticles or combination thereof on a surface thereon of the male or female part of the tag, which is pressed into the skin so that the microneedles penetrate into the epidermis and dermis layers of the skin. The agent is then released into the animal from the microneedles and or microparticles and or nanoparticles or combination thereof at the site of contact into the epidermis and dermis layers of the skin.

Single or multi-dose delivery platform for veterinary applications

Compositions and methods for treating a cellulosic substrate to impart water resistance are disclosed herein. The compositions are waxy solids that include a mixture of a fluorowax and a hydrocarbon wax. The compositions are applied to cut edges of a cellulosic substrate, such as a wood-based flooring material, to impart water resistance to the cellulosic substrate. The compositions and methods are useful on a wide range of wood-based flooring materials, including hardwood, laminate, and engineered wood flooring.

Water-repellant wax compositions and applications thereof

Disclosed herein are detachment mechanisms for vaso-occlusive devices that allow for rapid operator-controlled release of the vaso-occlusive device into the selected site. Also disclosed are vaso-occlusive assemblies comprising these detachment mechanisms and methods of using these detachment mechanisms and vaso-occlusive assemblies.

Detachment mechanisms for implantable devices

The present invention provides fluorinated compounds as well as dispersions of the fluorinated compounds. The fluorinated compounds described herein, in some embodiments, can be applied substrates such as textiles, including carpet and other floor coverings.

Stain repellent compositions and applications thereof

A satiation device is described which includes a sheath or liner extending from the proximal or middle stomach to the distal antrum. Food ingested by the patient passes through the sheath or liner, thereby minimizing contact between the ingested food and the stomach. It is believed that over time, reduced contact between food and the stomach will result in decreased Ghrelin production by the patient and a consequent decrease in appetite. In some embodiments, the satiation device may also include a proximal pouch and/or a distal bypass tube.

Gastro-esophageal implants

A method for controlling appetite by means of a satiation device is disclosed. The device, which includes a flexible webbing defining proximal and distal openings and a biasing structure, is attached to the patient's stomach with the proximal opening positioned adjacent and below the patient's gastro-esophageal junction. The biasing structure imparts pressure against the wall of the patient's stomach adjacent the gastro-esophageal junction.

Implantable devices having a radially expandable barrier and related methods of use

Disclosed are a system and method for performing a medical procedure using direct percutaneous access of an aorta. A main sheath is introduced through an incision formed in proximity to the sternum, and positioned along (and preferable against) a posterior portion of the sternum. Instruments passed through the main sheath are used to form a purse-string suture in an exterior wall of the aorta. An opening is formed in the wall of the aorta in a region encircled by the purse-string suture, and a distal end of an introducer sheath is advanced through the opening into the aorta. A medical procedure, which may be a transcatheter aortic valve replacement, is performed using instruments passed through the introducer sheath into the aorta. After the medical procedure, the introducer sheath is withdrawn from the aorta and, as the introducer sheath is withdrawn, the purse-string suture is tightened to close the opening.

Direct aortic access system for transcatheter aortic valve procedures

An intestinal implant includes a proximal anchor self-expandable from a radially compressed position to a radially expandable position for engagement with a wall of the intestinal lumen and a flexible sleeve coupled to the anchor. The sleeve is implanted with the anchor downstream from the pylorus and the sleeve extending further downstream through the intestinal lumen.

Intestinal sleeves and associated deployment systems and methods

A device for delivering an occlusive element includes an elongate sheath having a lumen therein. An elongate core member is disposed within the lumen and is formed from a proximal portion and distal portion connected via a joint. The distal portion of the elongate member includes a severable junction secured to the occlusive element. A marker coil is coaxially arranged around the distal portion of the elongate core member and is partially disposed inside the sheath lumen. A coil member is coaxially arranged around the distal portion of the elongate core member and coaxially arranged around at least a portion of the marker coil extending outside the lumen of the sheath. The coil member is secured at a distal end thereof to the distal portion of the elongate core member. The device resists axial compression while allowing for radial bending.

Vaso-occlusive delivery device with kink resistant, flexible distal end

The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.

Method and apparatus for retaining medical implants within body vessels

A device for inducing weight loss in a patient includes a tubular prosthesis positionable at the gastro-esophageal junction region, preferably below the z-line. In a method for inducing weight loss, the prosthesis is placed such that an opening at its proximal end receives masticated food from the esophagus, and such that the masticated food passes through the pouch and into the stomach via an opening in its distal end.

Gastrointestinal implants

Satiation pouches and methods of use

Growing community of inventors

Santa Rosa, CA, United States of America

Michael Scott Williams