Morningside Venture Investments Limited

Xtract Medical, Inc.

Other

Penumbra, Inc.

Revelle Aesthetics, Inc.

Abstract Ice, Inc.

Signum Surgical Limited

Nc8, Inc.

Michael Schaller

Jorge Gamba

Eric Sauvageau

Joshua Makower

Jonathan L Podmore

Andrew Lewis Johnston

Pablo Acosta

Earl A Bright, Ii

Theodore W Ketai

Kevin W Gelston

John Hanley

William Sauway Law

Bryan Hartley

Bryce Peterson

Moshe Zilversmit

Eoin Bambury

Todd Stevenson

Bryce Edmund Peterson

Ciaran O'Sullivan

Scott Early

David Perez

A containing element is used to capture material in a blood vessel for removal. The containing element is advanced through the blood vessel or a catheter in a constricted configuration. A control body is coupled to the containing element which assists moving the containing element. In some embodiments, the containing element is used for restricting blood flow within a vessel.

Devices and methods for removing material from a patient

Described herein are methods for making clear ice. In one embodiment, a method for making clear ice includes providing a mold of any of the embodiments described herein, optionally inserting a skewer through the mold, the skewer being coupled to an item; circulating, using fluid inlet and outlet valves, a fluid in a mold cavity defined by the mold; varying overtime one or both of: a temperature of the cooling apparatus or a fluid flow rate, through the fluid inlet valve, as a percentage of max flow; and optionally retracting the skewer when the ice formation encases at least a portion of the item. In some embodiments, the method optionally includes a period of flow reversal, such that the fluid inlet valve becomes the fluid outlet valve and the fluid outlet valve becomes the fluid inlet valve. In some embodiments, the method optionally includes releasing the ice from the mold.

Systems and methods for creating clear ice

A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.

Transdermal drug delivery devices and methods

Systems and methods for treating cellulite including an apparatus that applies or a method involving separating septa to eliminate or reduce the appearance of cellulite. In one approach, an interventional tool is placed between tissue layers to engage and treat septa connecting tissue layers between which fat deposits are contained.

Cellulite treatment system

A containing element is used to capture material in a blood vessel for removal. The containing element is positioned within a constraining catheter while it is advanced through the blood vessel. A filament is coupled to the containing element which assists in opening and/or closing the containing element.

An implantfor closing an opening in tissue such as a fistula or a sinus comprises a coil having a substantially uniform outer diameter. The coil forms an internal passage having a diameter that tapers from a distal end to a proximal end. The implantmay be delivered using a non-tapered driver coil

Implant for closing an opening in tissue

Described herein are devices and methods for creating a capsulorhexis. In some embodiments, the device includes a template with a tearing profile, which, when placed against the capsular bag, defines a perimeter of a capsulorhexis. In some embodiments, the device further includes rigid sections and bendable sections which are configured to transition the template between a first bent configuration for insertion through a corneal incision and a second unbent configuration for creation of the capsulorhexis. In some embodiments, the device further includes connecting elements which enter through the corneal incision and, when manipulated, transition the device between the first bent configuration and the second unbent configuration. In some embodiments, the connectors are configured to impart a downward force on the template and thus the capsular bag during the capsulorhexis creation.

Devices and methods for creating a capsulorhexis

Cellulite treatment system and methods

Growing community of inventors

Louisville, CO, United States of America

Michael Schaller