Waters Technologies Corporation

Michael S Young

Erin E Chambers

Claude R Mallet

Stuart A Oehrle

Ziling Lu

Diane Diehl

Jeffrey Mazzeo

The technology of the present application is directed to methods and kits for detecting and quantifying a non-polar analyte in a plant-derived sample. The technology uses a simple extraction, e.g., a liquid-liquid extraction (LLE) or solid-phase extraction (SPE), to enrich a sample for a non-polar analyte of interest and to remove contaminants. After the extraction and clean-up steps, liquid chromatography and mass spectrometry are used to detect the non-polar analyte. In one embodiment, acequinocyl and/or its derivatives is analyzed using liquid chromatography and tandem mass spectrometry (LC-MS/MS) and the improved LC-MS/MS conditions allows detection limits of acequinocyl and/or its derivatives of 50 ppb or less.

Methods for detecting and quantifying non-polar analytes with high sensitivity

Systems, methods and compositions for the purification, separation and analysis of anionic compounds, including polyanionic compounds are disclosed.

Methods for separating and analyzing anionic compounds

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Bellingham, MA, United States of America

Michael S Young