California Institute of Technology

Other

University of Florida Research Foundation, Incorporated

Aerovironment, Inc.

Competitive Technologies of Pa, Inc.

Michael S Freund

Nathan S Lewis

Shawn M Briglin

Erik J Severin

Adam J Matzger

Charles R Martin

Gregory S Ferguson

Eiichi Shoji

David T Mitchell

Mong-Tung Lee

Chen-Chan Hseuh

Gang Liu

Lisa M Regalla

Phil Tokumaru

An article of manufacture includes a rigid plate, first and second tab members defined by a pair of substantially diametrically-opposed U-shaped apertures within the plate, and a third tab member defined by a U-shaped aperture proximal to the first and the second tab members. The article of manufacture can be used as an active exhaust defeat device, providing the capability of locking a butterfly valve of a vehicle active exhaust system in a desired orientation. Although the butterfly valve is locked, which may be a non-standard exhaust configuration, the article of manufacture provides that vehicle error codes specific to an exhaust valve actuator are avoided.

Systems and methods for controlling vehicle exhaust output

Methods, systems and sensor arrays are provided implementing techniques for detecting an analyte in a fluid. The techniques include providing a sensor array including at least a first sensor and a second sensor in an arrangement having a defined fluid flow path, exposing the sensor array to a fluid including an analyte by introducing the fluid along the fluid flow path, measuring a response for the first sensor and the second sensor, and detecting the presence of the analyte in the fluid based on a spatio-temporal difference between the responses for the first and second sensors.

Use of spatiotemporal response behavior in sensor arrays to detect analytes in fluids

Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.

Use of an array of polymeric sensors of varying thickness for detecting analytes in fluids

Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.

Spatiotemporal and geometric optimization of sensor arrays for detecting analytes fluids

Disclosed is a method of preparing self-assembled monolayers on a metal comprising electrolyzing a thiosulfate compound in a solvent, where the electricity for the electrolysis is applied at a voltage for a period of time.

Electrochemically directed self-assembly of monolayers on metal

Sensor systems and sensing methods for detecting one or more analytes in a fluid. A sensor includes a polymer capable of undergoing a proton-coupled redox reaction. The polymer includes a plurality of reactive substituents capable of undergoing a reaction with an analyte. Upon exposure of the sensor to a fluid containing the analyte, a response is detected based on a change in the pK of the polymer.

Sensors and sensing methods for detecting analytes based on changes in pKa of a sensing polymer

Sensors, sensor arrays and sensing methods provide for detection of a chemical analyte in a fluid. Sensors include a plurality of conductive and nonconductive regions in contact with a measuring apparatus. One or more sensors include a plurality of particles that include a metallic core. Preferably, the particles also include one or more capping ligands coupled to the metallic core. Exposure of the sensors to a fluid containing a chemical analyte causes the analyte to react with the metal core, preferably by displacing one or more of the capping ligands. The chemical analyte can be detected based on a change in electrical or optical properties of the sensors.

Nanoparticle-based sensors for detecting analytes in fluids

A sensor array for detecting a microorganism comprising first and second sensors electrically connected to an electrical measuring apparatus, wherein the sensors comprise a region of nonconducting organic material and a region of conducting material compositionally that is different than the nonconducting organic material and an electrical path through the regions of nonconducting organic material and the conducting material. A system for identifying microorganisms using the sensor array, a computer and a pattern recognition algorithm, such as a neural net are also disclosed.

Sensor arrays for detecting microorganisms

A sensor array for detecting analyte in a fluid. The sensor comprises a substrate having an array of sensors. Each sensor comprises a combination of a first organic material at a concentration and a second organic material at a concentration, wherein the first organic material is different from the second organic material. The sensor array further includes a detector operatively associated with each said sensor. The sensor array is built from a feedstock of organic materials such that the number of sensors is greater than the number of different organic materials which form the sensors.

Sensor arrays for detecting analytes in fluids

A sensor array for detecting an analyte in a fluid, comprising at least first and second chemically sensitive resistors electrically connected to an electrical measuring apparatus, wherein each of the chemically sensitive resistors comprises a mixture of nonconductive material and a conductive material. Each resistor provides an electrical path through the mixture of nonconductive material and the conductive material. The resistors also provide a difference in resistance between the conductive elements when contacted with a fluid comprising an analyte at a first concentration, than when contacted with an analyte at a second different concentration. A broad range of analytes can be detected using the sensors of the present invention. Examples of such analytes include, but are not limited to, alkanes, alkenes, alkynes, dienes, alicyclic hydrocarbons, arenes, alcohols, ethers, ketones, aldehydes, carbonyls, carbanions, polynuclear aromatics, organic derivatives, biomolecules, sugars, isoprenes, isoprenoids and fatty acids. Moreover, applications for the sensors of the present invention include, but are not limited to, environmental toxicology, remediation, biomedicine, material quality control, food monitoring and agricultural monitoring.

Chemical sensors for detecting analytes in fluids comprise first and second conductive elements (e.g. electrical leads) electrically coupled to and separated by a chemically sensitive resistor which provides an electrical path between the conductive elements. The resistor comprises a plurality of alternating nonconductive regions (comprising a nonconductive organic polymer) and conductive regions (comprising a conductive material) transverse to the electrical path. The resistor provides a difference in resistance between the conductive elements when contacted with a fluid comprising a chemical analyte at a first concentration, than when contacted with a fluid comprising the chemical analyte at a second different concentration. Arrays of such sensors are constructed with at least two sensors having different chemically sensitive resistors providing dissimilar such differences in resistance. Variability in chemical sensitivity from sensor to sensor is provided by qualitatively or quantitatively varying the composition of the conductive and/or nonconductive regions. An electronic nose for detecting an analyte in a fluid may be constructed by using such arrays in conjunction with an electrical measuring device electrically connected to the conductive elements of each sensor.

Growing community of inventors

Altadena, CA, United States of America

Michael S Freund