Cambrex Charles City, Inc.

Theravance Biopharma Antibiotics IP, LLC

Michael Robert Tracey

Pär Holmberg

Zhiming Eric Dong

Weijiang Zhang

Junning Lee

Jan-Erling Bäckvall

Belén Lindberg Martín Matute

Antonio Bermejo Gómez

Belén Lindberg Martin Matute

Antonio Bermejo GÓMEZ

There is provided a novel process for the preparation of a compound of formula (I), wherein Ris as described in the description, by demethylation of a corresponding O-methyl derivative. 

Process for preparing hydromorphone and derivatives thereof

There is provided a novel process for the preparation of a compound of formula I, wherein R, Rand Rare as described in the description, by conversion of a corresponding allylic alcohol. 

Preparation of saturated ketone morphinan compounds by catalytic isomerisation

There is provided a novel process for the preparation of a hydrocodone salt. In particular, there is provided a novel process for the preparation of a free-flowing slurry of a hydrocodone salt, for example, a free-flowing slurry of hydrocodone bitartrate hemipentahydrate.

Process for the formation of hydrocodone bitatrate

The invention relates to a crystalline form of a triethylamine salt of (2Z)-2-(2 -amino-5-chlorothiazol-4-yl)-2-(3-N-tert-butoxycarbonylaminopropoxyimino)acetic acid. The invention also relates to processes and intermediates for preparing the crystalline form. The crystalline form is useful as an intermediate for preparing cross-linked glycopeptide-cephalosporin antibiotics.

Crystalline form of a substituted thiazolylacetic acid triethylamine salt

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Charles City, IA, United States of America

Michael Robert Tracey