Biologistex Ccm, LLC

Biolife Solutions Incorporated

On Semiconductor Trading, Ltd.

Michael Rice

Bruce McCormick

Aby J Mathew

Dominic M Clarke

Ian B Nicoud

Robert L Brennan

Hamid Sheikhzadeh-Nadjar

Kevin O'Donnell

Aby J Matthew

In some embodiments, alerts are sent to appropriate parties if an insulated container is not properly packed out to insure the approximate safe temperature of the materials. In other embodiments, a countdown timer is used to keep track of the time that the biologic has been in transit, and ensure that the amount of time does not exceed the known shelf life of the biologic. In still other embodiments, the payload container is equipped with its own sensors, such as temperature sensors, and communications devices, such as a close range communication device, capable of transmitting information regarding a range of parameters, including, but not limited to, temperature, humidity, location and time, from the payload container to an end user. In other embodiments, shielding and/or radiation sensors are included in insulated shipping or storage containers, or payload containers, to shield and monitor the radiation exposure of the payload.

Biologic stability, delivery logistics and administration of time and/or temperature sensitive biologic based materials

Provided are apparatuses for cryopreserving cells which include a vessel comprising a biocompatible substrate, wherein the vessel further comprises an interior and an exterior, and a mechanical ice nucleating device disposed in or on the vessel interior for initiating ice crystal formation. Also provided are kits comprising one or more apparatuses for cryopreserving cells and a biopreservation medium. Further provided are compositions comprising a vessel for holding cells, a mechanical ice nucleating device, a biopreservation medium, and cells disposed in the vessel. The apparatuses, kits, and compositions of the invention can optionally include an insulating material which is disposed on all or a portion of the vessel.

Apparatuses and compositions for cryopreservation of cellular monolayers

The present invention relates to materials and methods for hypothermic collection of whole blood, and components thereof, which can extend the holding time of blood beyond the current useable limit. Additionally, blood can be drawn directly into a hypothermic preservation solution without the addition of standard anticoagulants. This is enabled by providing sustained cellular viability under hypothermic conditions using a nutrient matrix devoid of animal proteins and containing energy substrates, free-radical scavengers, and impermeants that is ionically balanced for storage of biologic materials at low temperatures to prevent cellular stress-induced apoptosis.

Materials and methods for hypothermic collection of whole blood

A method and system for managing physiological systems is provided. The physiological system management (PSM) system includes one or more signal acquisition blocks to collect physiological information. The PSM system includes oversampled filterbanks for transferring one or more input signal related to the physiological information into subband signals, and a subband processing scheme for processing the outputs from the oversampled filterbanks for event detection in one or more physiological systems. The PSM system includes an adaptive controller which decides on the proper control measure and delivers the measure to the one or more physiological systems.

Method and system for managing physiological system

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Woodinville, WA, United States of America

Michael Rice