Abs Global, Inc.

Genus, Inc.

Michael Reid Botts

Matthias Wagner

Elon Roti-Roti

Nicole Cray

Domenic Busa

Johnathan Parker

Gary Klas

Technologies for assessing, quantifying and isolating sperm cell populations and/or subpopulations having specific genetic signatures are provided, as well as methods and systems to assess the efficacy of chromosomal differentiation processes. Compositions for identification and differentiation of X-chromosomes and Y-chromosomes in DNA are also provided.

Methods and systems for assessing and/or quantifying sperm cell subpopulations bearing a specific genetic signature

An integrated system and method for preparing sperm cells to improve their survivability during cryopreservation are described herein. The system features a vessel, a controlled dispenser, and a dispense tube. The dispense tube has a first end fluidly connected to the dispenser and a second end disposed inside the vessel. The second end can be submerged in the sperm cell fluid. The controlled dispenser may be a syringe pump that includes a syringe for containing a cryoprotectant and a pushing mechanism for displacing the syringe. The syringe pump is configured to discharge the cryoprotectant through the dispense tube and into the vessel, thereby dispensing the cryoprotectant into the sperm cell fluid. Mixing of the fluids is achieved using a shaker table agitation.

System and process for continuous addition of cryoprotectant

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DeForest, WI, United States of America

Michael Reid Botts