Flagship Pioneering Innovations Vi, LLC

Michael Raymond Retchin

Avak Kahvejian

Nicholas McCartney Plugis

Fabian Alexander Wolf

Poorya Hosseini

A database processing system performs a first database access call accessing a first construct representing a differential component amount between a normal and different state. This identifies a plurality of components and, for each, a corresponding first association between (a) a change in amount of the respective component in a first plurality of first component datasets and a second plurality of second component datasets and (b) a change in state between the normal and different state. A second database access call accesses a second construct representing a measure of differential component amount between a native and exposed sample. The second construct identifies all or a portion of the plurality of components and, for each, a corresponding second association between a change of amount of the respective component between a third and fourth plurality of component datasets. The first associations and corresponding second associations determine whether the entity affects the transition.

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Columbus, OH, United States of America

Michael Raymond Retchin