Idexx Laboratories, Inc.

Michael Randolph Atkinson

Murthy V S N Yerramilli

Mahalakshmi Yerramilli

Kwok Kam Yeung

Murthy V Yerramilli

Mahalakshimi Yerramilli

Yerramilli V S N Murthy

Yerramilli Vsn Murthy

Timothy Smith

Gerard Simon

Mahalakshmi Padmanabhan

Murthy Vsn Yerramilli

Mahalakshni Yerramilli

Yerramilli VSN Murthy

This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.

Markers for renal disease

A portable fluid filtration system. The portable filtration system includes a trailer having a ceiling with a predetermined height, and having an openable and closeable ceiling passage. One or more filter assembles are disposed in the trailer. Each filter assembly includes a filter base and a filter cartridge connectible and dis-connectible to the filter base. The filter cartridge has a height such that when it is disposed on the filter base, the filter cartridge extends beyond the predetermined height of the trailer ceiling. The system also has a fluid input/output assembly disposed in the trailer and fluidically connected to the at least one filter assembly, the liquid input/output assembly being for receiving fluid to be cleaned and inputting it to the at least one filter assembly and for receiving filtered fluid from the filter assembly and for outputting it. The system further has a rotatable, extendable filter cartridge mover disposed in the trailer, for connecting and disconnecting the filter cartridge to the filter base.

Mobile filtration technology

Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (&#x2014;SH) group or hydroxyl (&#x2014;OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.

Methods for detecting symmetrical dimethylarginine

The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.

Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds

A method for determining the amount of NT-proBNP in blood samples from animals. The method includes detecting degradation products of NT-proBNP by various methods, including using antibodies, kits and device.

Detection of degradation products of canine NT-proBNP

A method for determining the amount of NT-proBNP in blood samples from felines. The method includes detecting degradation products of feline NT-proBNP by various methods, including using antibodies, kits and devices.

Growing community of inventors

Gorham, ME, United States of America

Michael Randolph Atkinson