Seahorse Bioscience

Flir Systems Boston, Inc.

Thermogenic Imaging, Inc.

Agilent Technologies, Inc.

Michael R Sweeney

Andy C Neilson

Jay S Teich

Geoff Uhl

James D Orrell, Iii

John M Hopkins

Michael W Oster

Marc Samson

Marc Sampson

A method of analyzing cells disposed in media within a vessel includes the steps of providing a vessel having an original volume of media about the cells, reducing the original volume of media about at least a portion of the cells to define a reduced volume of media, and analyzing a constituent related to the cells within the reduced volume of media. An apparatus for analyzing cells includes a stage adapted to receive a vessel holding cells and a volume of media, a plunger adapted to receive a barrier to create a reduced volume of media within the vessel including at least a portion of the cells, the barrier adapted for insertion into the vessel by relative movement of the stage and the plunger, and a sensor in sensing communication with the reduced volume of media, wherein the sensor is configured to analyze a constituent disposed within the reduced volume.

Method and device for measuring multiple physiological properties of cells

Apparatus and methods for performing calorimetry. The apparatus include optical devices for detecting thermal processes and multiwell sample plates for supporting samples for use with such optical devices. The methods include measurement strategies and data processing techniques for reducing noise in measurements of thermal processes. The apparatus and methods may be particularly suitable for extracting thermal data from small differential measurements made using an infrared camera and for monitoring chemical and physiological processes.

Apparatus and methods for infrared calorimetric measurements

Growing community of inventors

Pelham, NH, United States of America

Michael R Sweeney