University of Colorado

Colorado State University Research Foundation

Michael R Lappin

Steven Dow

Lyndah Chow

Daniel P Regan

Thomas J Anchordoquy

William H Wheat

The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (TLR3) and toll like receptor 9 (TLR9) ligands; and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal surfaces. In further aspects, disclosed compositions are administered to a mammal in conjunction with an antigen to enhance the immune response of the mammal to the antigen.

Growing community of inventors

Fort Collins, CO, United States of America

Michael R Lappin