Seedlings Life Science Ventures, LLC

Intarcia Therapeutics, Inc.

Other

Mitralign, Inc.

Ivoclar Vivadent Ag

Onpoint Systems, LLC

Ventriflo, Inc.

Edwards Lifesciences Corporation

I2o Therapeutics, Inc.

Michael R Cole

James M Sellers

Keith Rubin

Mathew S Cardinali

Michael Perlman

Sidney Perlman

Jay S Smith

Amy K Whitson

Klaus Lessnau

Stephen Jay Lowenstein

Jason Robinson

Michael W Sutherland

Steven D Cahalane

Aaron M Call

Christopher Lee

Megan E Holmes

Gregory Kenny

Ken Solovay

Timothy VanderMey

Matthew Weber

Roger D Greeley

Scott D Lautenbach

Lawrence M Kuba

Kenneth S Solinsky

Douglas E Vincent

Xinnakone Vivathana

Kristen Lomastro

Scott Sterling

Christopher C Lee

Gregory J Kenny

David Olney

Lars Erickson

Rehan Azeem

August Kawski

Douglas B Snell

James Donnelly

Phoebe Erickson

Laura S Cleminson

Matthew S Cardinali

Jason H Robinson

Timothy Vandermey

Mathew Cardinali

Michael Ellis Perlman

A pulsatile fluid pump apparatus includes an integral pump assembly employing a flexible diaphragm in a diaphragm assembly; a pulsatile fluid pump system including a control housing, for removably receiving the integral pump assembly, the control housing and the integral pump assembly being configured for operation, in a first mode, so that the pulsatile fluid pump system reciprocally actuates the diaphragm assembly to cause pumping automatically; and a manual driver assembly, wherein the integral pump assembly is configured, in a second mode, in the absence of actuation of the diaphragm assembly by the pulsatile fluid pump system, to removably receive the manual driver assembly to support manual actuation and operation of the diaphragm assembly.

Manual driver assembly for a pulsatile fluid pump

A system and accompanying assembly, of integrated or modular construction, for inflating and monitoring pressure within a retaining cuff including a housing having a pressure chamber connected in fluid communication with a fluid pressure source and a fluid communicating connection with the retaining cuff. Associated control circuitry includes a pressure sensor disposable in fluid communication with the pressure chamber and the retaining cuff, via the fluid communicating connection and structured to concurrently determine and monitor pressure within the pressure chamber and the retaining cuff. The control circuitry is cooperatively structured with the pressure sensor and other operative components to establish dynamic multilevel sampling capabilities, calibration parameters stored within the control circuitry prior to use and limited or single use capabilities of the assembly.

System and assembly for inflating and monitoring pressure within a retaining cuff

Implant placement guide

Implant removal tool and assembly

Implant removal tool

Devices, methods, and systems are provided for placing an implant into a patient and removing it therefrom.

Implant placement and removal systems

A minimally invasive catheter and methods are provided for adjusting the chordae associated with an atrio-ventricular valve and for modifying the geometry of selected cardiac chambers. Clamps carried by the catheter are part of a prosthetic clamp assembly that includes the clamps and a cord attached to each of the clamps. The cord length can be adjusted after the clamps are attached to tissue. The clamps can be operated simultaneously or independently.

Catheter system for selectively manipulating and connecting cardiac tissues

Dog Collar

A dental blank holder for the manufacture of dental articles. The dental blank holder can include a frame configured to cooperate with a blank holder of a dental mill. The frame can includes an inner periphery and an outer periphery, the inner periphery including a plurality of receiving walls forming receiving spaces, each receiving space configured to receive a dental blank. The dental blank holder may also include a movable arm configured to form a plurality of locking walls, each locking wall configured to enclose a corresponding receiving space, the movable arm including at least one biasing member configured to apply an individual force toward each receiving space such that each of the dental blanks is held in the receiving spaces for a milling process.

Dental blank holder

A tissue anchoring system includes a tissue anchor member that is suitable for anchoring against tissue. The system also includes a tensioning member operatively connected to the anchor member such that the anchor member can slide relative to the tensioning member, the tensioning member capable of being pulled to cause the anchor member to move relative to the tensioning member into a position seated against the tissue. A hand operated deployment catheter is operable to extend and deploy the anchor member therefrom. The deployment catheter includes a rotatable member about which the tensioning member is routed and a clutch assembly for limiting tension within the tensioning member to prevent the deployed anchor from being pulled through the tissue.

Hand operated device for controlled deployment of a tissue anchor and method of using the same

Growing community of inventors

Stratham, NH, United States of America

Michael R Cole