Basf Se Corporation

Basf Aktiengesellschaft

Merial Limited

Abbott Laboratories Corporation

Reinhard, Robert

Hamprecht, Gerhard

Puhl, Michael

Seitz, Werner

Michael Puhl

Gerhard Hamprecht

Robert Reinhard

Deborah L Culbertson

Michael Rack

Hassan Oloumi-Sadeghi

Douglas D Anspaugh

Cyrill Zagar

Henricus Maria Martinus Bastiaans

Wolfgang Von Deyn

Henry Van Tuyl Cotter

Norbert Götz

Thomas Schmidt

Werner Seitz

Matthias Witschel

Wolfgang Siegel

Joachim Dickhaut

Ernst Baumann

Markus Kordes

Michael Keil

Bernd Wolf

Thomas Grote

Liliana Parra Rapado

Olaf Menke

Matthias Pohlman

Andreas Landes

Wassilios Grammenos

Joachim Rheinheimer

Klaus Ditrich

Bernd Sievernich

Jan Klaas Lohmann

Karsten Koerber

Jochen Dietz

Karl-Otto Westphalen

Helmut Walter

Ulf Misslitz

Peter Plath

Thomas Zierke

Bernd Mueller

Guido Mayer

Bernd Müller

Hansgeorg Ernst

Michael Breuer

Norbert Gotz

Frank Schieweck

Klaus Grossmann

Ingo Sagasser

Toni Bucci

David G Kuhn

Melanie Weingarten

Franz-Josef Braun

Michael Hofmann

Livio Tedeschi

Christopher Koradin

Giovanni Cipolletti

Liana Salsini

Delphine Breuninger

Gessica Laudati

Steffen Gross

Klaus Groβmann

Thorsten Volk

Jens Renner

Alexander Korte

Sarah Ulmschneider

Marco Coppola

Marianna Vrettou

Florian Kaiser

Heinz Hillen

Andreas Keller

Arun Narine

Kai-Uwe Baldenius

Rene Lochtman

William Karl Moberg

Thomas Ehrhardt

Ronan Le Vezouet

Nina Gertrud Bandur

Prashant Deshmukh

Michael Frank Treacy

Frank Stelzer

Tao Qu

Martin Viertelhaus

Karsten Körber

Jürgen Langewald

Hartwig Schroeder

Eike Hupe

Vaidotas Navickas

Sarah Thompson

Stefan Hergenr&ouml;der

Cecille Ebuenga

Andrea Vescovi

Sebastian Wloch

Peter Oedman

Steffen Groβ

Jacek Malisz

Pepa Dimitrova

Toralf Kühn

Helmut Schiffer

Johann-Christian Zechel

Deborah L Culberston

Chung Huan Wong

The present invention relates to a process for the production of chromanol and 2-methyl-1,4-naphthoquinone derivatives, more specifically to a process for preparing a compound of the general formula (I) or (II) wherein the variables are as defined in the claims and the description.

Synthesis of chromanol and 2-methyl-1,4-naphthoquinone derivatives

The present invention relates to a process for the production of chromanol derivatives, more specifically to a process for preparing a compound of the general formula (I) wherein R, Rand Rindependently of each other are selected from hydrogen and methyl, Ris selected from hydrogen and C-C-alkanoyl, and X is selected from C-C-alkyl and C-C-alkenyl.

Synthesis of chromanol derivatives

The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2&#x2032;-FL raw material, which contains 2&#x2032;-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2&#x2032;-FL, where the method comprises a)providing a solution of the 2&#x2032;-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2&#x2032;-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2&#x2032;-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).

Method for obtaining crystalline 2'-fucosyllactose

The present invention relates to a process for the production of chromanol derivatives, more specifically to a process for preparing a compound of the general formula I wherein R, Rand Rindependently of each other are selected from hydrogen and methyl, Ris selected from C--C-alkyl, and X is selected from C-C-alkyl and C-C-alkenyl. 

This invention describes new hydrated and anhydrous polymorphs of 2'-O-fucosyllactose (2&#x2032;FL): Polymorph A 2&#x2032;FL-3/2HO, Polymorph B 2TL-5/2 HO and anhydrous Polymorph C. There is also a description of the methods for obtaining them, and of a new method for preparing Polymorph I already known in the literature.

Hydrated and anhydrous polymorphs of 2'-O- fucosyllactose and their production methods

The present invention relates to a method for preparing 2'-O-fucosyllactose, the 2&#x2032;-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C-C-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base.  In the formulae (I) and (II), the variables are each defined as follows:

Method for preparing 2'-O-fucosyllactose

Hydrated and anhydrous polymorphs of 2'-O-fucosyllactose and their production methods

This invention describes new hydrated and anhydrous polymorphs of 2'-0-ficosyllactose (2&#x2032;FL): Polymorph A 2&#x2032;FL-3/2HO, Polymorph B 2TL-5/2HO and anhydrous Polymorph C. There is also a description of the methods for obtaining them, and of a new method for preparing Polymorph I already known in the literature.

The present invention relates to biocatalytic methods, comprising purely enzymatic, mixed enzymatic-fermentative and purely fermentative methods, for the direct single-step conversion of L-fucitol to L-fucose, in order to easily obtain L-fucose at high amounts and levels of purity. Suitable recombinant microorganisms and fungi are further disclosed and also the use thereof in said method for the single-step conversion to L-fucose.

Biocatalytic production of l-fucose

N-Thio-anthranilamid compounds of formula (I) wherein A is A wherein the variables and the indices are as defined per the description, processes for preparing the compounds I, pesticidal compositions comprising compounds I, use of compounds I for the control of insects, acarids or nematodes, and methods for treating, controlling, preventing or protecting animals against infestation or infection by parasites by use of compounds of formula I.

N-Thio-anthranilamid compounds and their use as pesticides

The present invention relates to novel pyrazole compounds of the formulae I and II, to their salts and their N-oxides which can be used for combating or controlling invertebrate pests, in particular arthropod pests. The invention also relates to a method for controlling invertebrate pests by using these compounds. The present invention also relates to seed and to an agricultural and veterinary composition comprising said compounds. wherein 

Pyrazole compounds for controlling invertebrate pests

The present invention relates to the preparation of oxovinylionol and its O-protected derivatives of the formula I in which R is hydrogen or an OH protecting group, for example a group Si(R), by reacting a compound of the general formula II in which R has the meanings given above for formula I, i.e. &#x3b2;-vinyl ionol (formula II, R=hydrogen) or an O-protected derivative thereof (formula II, R&#x2550;OH protecting group) with an oxidant in the presence of at least one transition metal, where the oxidant comprises at least one oxygen-containing compound which is selected from among hydrogen peroxide and organic hydroperoxides.

Process for the preparation of oxovinylionol and its O-protected derivatives

The present invention relates to a process for the preparation of 2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]-hydroxylamine from the correspondingly substituted nitrobenzene compound.

Process for preparing substituted N-phenylhydroxylamines

N-Thio-anthranilamid compounds of formula (I)  

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Lampertheim, Germany

Michael Puhl