Genzyme Corporation

Michael Parrott

Alexander Hee-Hanson

Robert Wilson

Thomas Lever

Haiming Wu

Nicholas Harding

A medicament delivery device is described. The medicament delivery device includes a proximal end and a distal end defining a longitudinal axis; a body; and a button arranged at the proximal end and configured to actuate the medicament delivery device. The medicament delivery device further includes a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the button is not permitted to move along the longitudinal axis relative to the body, and a second position in which the button is permitted to move along the longitudinal axis relative to the body; a plurality of first indication elements circumferentially spaced around a first portion of the medicament delivery device; and a plurality of second indication elements circumferentially spaced around a second portion of the medicament delivery device.

Medicament delivery device

The application relates to a lock ring for a medicament delivery device. The lock ring comprises a hollow main body formed from a plurality of circumferentially extending portions. Each portion is defined between tool split lines defining circumferential ends of the portions. Each circumferential end of a portion is connected to an adjacent portion along a tool split line. The main body comprises a plurality of bearing elements configured to contact a body of a medicament delivery device. Each of the plurality of bearing elements is configured to form a low friction rotation interface. At least one of the plurality of bearing elements is formed proximate to one of the circumferential ends of a portion of the main body.

Lock ring for a medicament delivery device

A medicament delivery device is described. The device includes a body comprising a proximal end and a distal end; a needle for injecting medicament; an actuation member moveable relative to the body for actuating the device; a lock ring configured to rotate relative to the body between a first position in which the actuation member is not permitted to move relative to the body, and a second position in which the actuation member is permitted to move relative to the body; and a cap arrangeable in a capped position in which the cap abuts with and conceals the distal end of the body to conceal the needle; wherein when the cap is in the capped position the lock ring is in a first state in which the lock ring is in the first position and is not permitted to rotate towards the second position; and wherein moving the cap in a distal direction away from the distal end of the body along the longitudinal axis away from the capped position causes the lock ring to be in a second state in which the lock ring is permitted to rotate from the first position towards the second position.

A medicament delivery device for injecting medicament which has a body having a proximal end and a distal end, a needle for injecting medicament and an actuation member which is movable relative to the body. The actuation member is movable from a first position to a second position and movable from the second position to a dispensing position for dispensing medicament from the needle. The second position is proximal of the first position. The medicament delivery device further has a cap which is removably attached to the medicament delivery device. The cap has a portion configured to prevent movement of the actuation member from the first position to the second position when the cap is attached to the medicament delivery device.

An injection device comprises: an injection device body; a needle shroud comprising a shroud pin; and a collar rotatable with respect to the injection device body and comprising a cam track. During retraction of the needle shroud, a first portion of the cam track guides the shroud pin to a hold position and cause the collar to rotate relative to the injection device body from a first position to a second position. During a subsequent extension of the needle shroud, a second portion of the cam track guides the shroud pin from the hold position to a final position and causes the collar to further rotate relative to the injection device body from the second position to a third position, the second portion comprising a blocking portion configured to prevent extension of the needle shroud from the injection device body when the collar is held in the second position.

Needle shroud latch for injection devices

A damping device for a medicament delivery device, comprising: a generally cylindrical first collar; a housing comprising a generally annular cavity configured to receive at least a portion of the first collar; wherein the first collar is configured to be rotatable relative to the housing about a central longitudinal axis of the damping device, and wherein the cavity is configured to contain a fluid for impeding rotational movement of the first collar relative to the housing; and a sealing arrangement configured to fluidly seal an interface between the housing and the first collar.

Damping device for a medicament delivery device

A medicament delivery device comprising a body, a needle, and an actuation member movable proximally from an initial position to a protruded position, and distally from the protruded position to an actuation position. The device has a transfer member which is movable proximally between an extended and a retracted position. In the extended position the distal end of the transfer member protrudes from the body. One of the actuation member and the transfer member has a drive slot and the other of the actuation member and the transfer member comprises a protrusion located in the drive slot. The drive slot has a circumferentially-extending portion having an abutment surface. The protrusion engages the abutment surface to move the actuation member from the initial position to the protruded position.

A medicament delivery device includes a first component, a second component configured to be movable with respect to the first component, and a temperature-dependent interconnect configured to resist movement of the first component relative to the second component. The temperature-dependent interconnect includes an engagement member and a temperature-dependent material configured to engage each other. The temperature-dependent material has a temperature-dependent material characteristic such that the temperature-dependent material has (i) a first material characteristic at a first temperature of the temperature-dependent material to resist movement of the first component with respect to the second component, and (ii) a second material characteristic at a second temperature of the temperature-dependent material to allow movement of the first component with respect to the second component.

A medicament delivery device includes a needle being axially moveable from a retracted position to an exposed position. The device includes an actuation member configured to be movable to an actuation position to cause the needle to move from the retracted position to the exposed position. The device includes a locking member for preventing the movement of the actuation member to the actuation position, and a locking release member being axially moveable towards a proximal end of the medicament delivery device from a first position, in which the locking member is prevented from moving to a release position in which the actuation member is released for the movement of the actuation member to the actuation position, to a second position, in which the locking member is free to move to the release position in which the actuation member is released for the movement of the actuation member to the actuation position.

A medicament delivery device includes an actuator including an actuation member configured to be movable by a user to an actuation position to cause a dose of medicament to be dispensed from the medicament delivery device. The actuator is configured to be movable from a deactivated position in which a user is prevented from moving the actuation member to the actuation position to an activated position in which the actuation member is released for movement by a user to the actuation position. The device includes a temperature-dependent actuator configured to move the actuator from the deactivated position to the activated position in response to a change in temperature of the temperature-dependent actuator.

A medicament delivery device includes a needle disposed at a distal end of the medicament delivery device, a body for a syringe, and a needle cover axially movable relative to the body between an extended position in which the needle cover covers the needle and a retracted position for dispensing medicament from the medicament delivery device. The needle protruding from the distal end of the needle cover when the needle cover is in the retracted position. The medicament delivery device includes an actuation member configured to be movable from an initial position to an engaged position such that when the actuation member is in its initial position, the needle cover can be axially moved between its retracted position and its extended position, and when the actuation member is in its engaged position, the actuation member engages with the needle cover to hold the needle cover in its retracted position.

This application relates to an injector device for delivery of a medicament, particularly to an auto-injector device. According to a first aspect of this disclosure, there is described an injection device comprising: an injection device body; a needle shroud retractable into the injection device body comprising a shroud pin; a control spring coupled to the needle shroud and biased to cause the needle shroud to be at least partially extended from the injection device body in an initial position; and a collar rotatable with respect to the injection device body and comprising a cam track engageable with the shroud pin; a hold detent mechanism coupled to the cam track of the collar, wherein the hold detent mechanism is configured to: activate, when the needle shroud is retracted from a first position on the cam track into the injection device body to a hold position on the cam track, by engaging the shroud pin thereby creating a hold detent force opposite a control spring force caused by compression of the control spring during said retraction of needle shroud to said hold position; and deactivate, when the needle shroud is extracted from the hold position on the cam track subsequent to the retraction towards a second position on the cam track, by disengaging the shroud pin thereby releasing the hold detent force and enable the needle shroud to extend from the injection device body to the second position on the cam track; and wherein the hold detent mechanism further comprises a non-return surface configured to, subsequent to the extension of the needle shroud, prevent further retraction of the needle shroud into the injection device body along the cam track towards the hold position.

Collar hold detent mechanism and lock for injection devices

Some injection devices include an injection device body, a needle shroud retractable into the injection device body, a control spring coupled to the needle shroud and biased to cause the needle shroud to be at least partially extended from the injection device body in an initial position, and a hold detent mechanism coupled to at least the needle shroud. The hold detent mechanism is configured to (i) activate, when the needle shroud is retracted from the initial position into the injection device body to a hold position, to create a hold detent force, and (ii) deactivate, when the needle shroud is extracted from the hold position subsequent to the retraction, to release the hold detent force and enable the needle shroud to extend from the injection device body to substantially the initial position.

Hold detent mechanism for injection devices

A medicament delivery device for reducing a force required to activate the device includes a needle disposed at a distal end of the device, a needle cover, and a body. The needle cover is axially movable relative to the body between an initial position in which the needle cover covers the needle and an activated position for dispensing a medicament. The needle protrudes from a distal end of the needle cover when the needle cover is in the activated position. The medicament delivery device includes a carrier configured to support a syringe. The carrier is disposed within the needle cover and includes a deformable element configured to change from a first configuration in which the deformable element is engaged with the needle cover to a second configuration in which the deformable element is not engaged with the needle cover.

Injector device

A medicament delivery device includes a needle disposed at a distal end of the medicament delivery device. The medicament delivery device includes a body for a syringe and a needle cover axially movable relative to the body between an extended position in which the needle cover covers the needle and a retracted position in which the needle protrudes from the distal end of the needle cover. The medicament delivery device includes a plunger axially movable relative to the body to dispense medicament from the medicament delivery device. The medicament delivery device includes a needle cover biasing mechanism configured to bias the needle cover distally from the retracted position to the extended position. The medicament delivery device includes a locking mechanism configured to be moved by the plunger from an initial configuration to an engaged configuration to prevent a distal movement of the needle cover biasing mechanism.

Growing community of inventors

Melbourn, United Kingdom

Michael Parrott