Washington University

Michael P Rettig

John F Dipersio

Allegra Petti

Timothy J Ley

Matthew Christopher

Among the various aspects of the present disclosure is the provision of methods and compositions for upregulating MHC class II in cancer cells (e.g., a hematological cancer cell). Also provided are methods of treatment for subjects suffering from hematological cancers, comprising administration of interferon-&#x3b3; (IFN-&#x3b3;). The methods of treatment provided herein may be particularly suitable for subjects who have received an allogenic transplant or have suffered a relapse.

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St. Louis, MO, United States of America

Michael P Rettig