Microfluidics International Corporation

Michael P Ratigan

John Michael Bernard

David G Harney

Jocemar Ramina

Marco G Catalani

Rachel Otte

Ahmad Shehata

Harshit Kumar Patel

The present disclosure provides apparatuses and methods related to a high pressure processing device that is configured to simplify batch processing. In an embodiment, a high pressure processing device includes a processing module configured to reduce a particle size of a material or achieve a desired liquid processing result for the material, a pump configured to pump the material to an inlet of the processing module, a recirculation pathway configured to recirculate the material from an outlet of the processing module back to the pump, an input device configured to receive at least one user input variable, and a controller configured to (i) determine a number of pump strokes for the pump based on the user input variable, and (ii) control the pump according to the determined number of pump strokes so that the material makes a plurality of passes through the processing module.

High-pressure fluid processing device configured for batch processing

Apparatuses and methods related to a high pressure fluid processing device having a dual check valve setup that can be quickly and easily maintained with replacement parts are disclosed herein. In a general example embodiment, a high pressure processing device includes a body including a first surface having a first recess, a second surface having a second recess, and a third surface having a third recess, a first subassembly at least partially inserted into the first recess of the body, the first subassembly including a first check valve, a second subassembly at least partially inserted into the second recess of the body, the second subassembly including a second check valve, and a third subassembly at least partially inserted into the third recess of the body, the third subassembly coupling the body to a fluid driving mechanism, wherein the first subassembly, second subassembly and third subassembly are configured to be independently attachable to and detachable from the first recess, second recess and third recess, respectively.

Apparatuses and methods using high pressure dual check valve

A new and innovative high-pressure priming valve is provided for use in high-pressure fluid systems that require a high level of fluid purity. The priming valve includes at least three ports, some of which are angled. The priming valve also includes a needle that variably blocks and unblocks a pathway to one of the ports between normal operation and a priming operation, respectively. The priming valve includes a sealing insert positioned below a stack of washers that maintain the needle's alignment in response to high fluid pressures exerted on the needle. The sealing insert helps prevent fluid from contacting the stack of washers, which helps prevent biological growth within the valve. The angled ports help facilitate priming valve drainage to further help prevent biological growth. By helping prevent biological growth, the sealing insert helps prevent fluid contamination and enables the priming valve to be utilized for high-purity fluid applications.

High-pressure priming valve

Apparatuses and methods related to a high pressure fluid processing device having a dual check valve setup that can be quickly and easily maintained with replacement parts are disclosed herein. In a general example embodiment, a high pressure processing device includes a body including a first surface having a first recess, a second surface having a second recess, and a third surface having a third recess, a first subassembly at least partially inserted into the first recess of the body, the first subassembly including a first check valve, a second subassembly at least partially inserted into the second recess of the body, the second subassembly including a second check valve, and a third subassembly at least partially inserted into the third recess of the body, the third subassembly coupling the body to a fluid driving mechanism, wherein the first subassembly, second subassembly and third subassembly are configured to be independently attachable to and detachable from from the first recess, second recess and third recess, respectively.

Growing community of inventors

Westwood, MA, United States of America

Michael P Ratigan