International Flavors & Fragrances Inc.

Michael P McLean

Mark A Sprecker

Mohamad I Farbood

Myrna L Hagedorn

Nicolas Kossiakoff

Lynda B McLean

Robert W Blocker

Augustine Yonghwi Kim

Mark Lawrence Dewis

Kwang-Pil Choi

John Lyons Buckley, Iii

The present invention is directed to the use of yeasts to produce spiroketal fragrance materials. The preferred yeasts used in the method of the invention areand

Process for the manufacture of spiroketals

Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the 'cis' isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the 'cis' isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&#x3b1;) of +58&#xb0; are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&#x3b1;) of +58&#xb0; are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain ofin a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.

Jasmonic acid and jasmonic acid ester stereoisomers and compositions

Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof

Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the &ldquo;cis&rdquo; isomer defined according the structure:

Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate

Growing community of inventors

Matawan, NJ, United States of America

Michael P McLean