Eli Lilly and Company

Other

Michael P Lynch

Daniel Jon Sall

Gerald Floyd Smith

Ho-Shen Lin

Minsheng Zhang

Richard Waltz Harper

Kumiko Takeuchi

Jefferson Ray McCowan

Robert J Foglesong

Mary George Johnson

Michael Lyle Denney

Nickolay Y Chirgadze

Alan David Palkowitz

Matthew Joseph Fisher

Jolie Anne Bastian

Michael Enrico Richett

Valentine Joseph Klimkowski

Jennifer Marie Tinsley

James R Beck

Shawn Christopher Miller

Todd Jonathan Kohn

Michael Robert Wiley

Gary D Crouse

Nicholas J Bach

Jeffery Dale Webster

Jeffrey Thomas Mullaney

John P Wright

The invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts, as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula (I), and the use of the compounds of formula (I) as thrombin inhibitors.

Antithrombotic agents

This application relates to novel compounds of formula I (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula I, and the use of defined compounds of formula I as thrombin inhibitors.

Thrombin inhibitors

This application relates to novel compounds of formula (I) (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula (I), and the use of the compounds of formula (I) as thrombin inhibitors.

This application relates to the use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents of diamines of formula I as defined herein. It also provides novel compounds of formula I, processes and intermediates for their preparation, and pharmaceutical formulations comprising the novel compounds of formula I.

Antithrombotic diamines

The present invention relates to novel phenylimidazolone compounds of the formula ##STR1## wherein A is a bond or C.dbd.T;

Intermediates for herbicidal phenylimidazolones

1,5-Disubstituted-1H-pyrazole-4-carboxamide derivatives, useful as herbicides and aquatic algicides.

Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides

The present invention is directed to herbicidal compounds of the formula ##STR1## wherein each R.sup.1 independently is halogen; R.sub.2 is halo or trifluoromethyl; and n is 1-5; with the provisos that when n is 1, R.sup.1 is other than fluorine, and when n is 2 and each R.sup.1 is chlorine, at least one R.sup.1 is located at a para or ortho position on the phenyl ring.

Herbicidal 5-halo-1-halophenyl-1H-pyrazole-4-carbonitriles

Growing community of inventors

Greenfield, IN, United States of America

Michael P Lynch