Cook Medical Technologies LLC

Cook Incorporated

University of Florida Research Foundation Inc

Med Institute Incorporated

Other

Cook Biotech, Inc.

William A. Cook Australia Pty. Ltd.

William Cook Europe Aps

Cook Regentee LLC

Cook Regentec LLC

Michael P DeBruyne

Siddharth Vad

Thomas A Osborne

Blayne A Roeder

William John Havel

Rick Hadley

Neal E Fearnot

Jarin A Kratzberg

Zachary Wagner

Tony C Hopkins

Richard Joel Melker

Gary J Miller

Jason A Mead

Benjamin Nickless

Peter F Gearen

Lisa Molitor

Jeffry Scott Melsheimer

Alan R Leewood

William A Cook

Mark Robert Frye

Jichao Sun

Lal Ninan

Clinton D Bahler

David Ernest Hartley

Erik Edelbo Rasmussen

Krasnodar Ivancev

Werner Dieter Ducke

Andrew K Hoffa

Frank J Fischer, Jr

William Kurt Dierking

Matthew S Huser

Per Hendriksen

Eugene Skelton

Edwin E Macatangay

Shyam Kuppurathanam

Thomas A Sos

John A DeFord

Wen Hong Neoh

Jay A Dittman

Ronan T Young

Aaron Barr

Anthony Wright

Brian D Choules

Sarah E Reeves

Erik Hughes

Peter R Uldall

Timothy A Chuter

Gregory D Elliott

Ashvin Lad

Micheal C Hoffa

Jarett Diamond

Matthew S Waninger

Konstantinos O Papazolgou

Natalie Jones

Frank J Fisher

Siddarth Vad

A device for introducing material into a body cavity is shown. The device includes a catheter with a distal tip. A first lumen extends through the catheter. The catheter is configured to faun a mist from liquid passed through the first lumen, for example including a misting nozzle in fluid communication with the first lumen and configured to provide a mist from a flow of liquid through the first lumen. An inflatable balloon may be included on the catheter to allow the user to isolate the portion of the body in which the material is introduced. Additional described features can provide for controlled deflection of a distal region of the catheter, guidewire or guide loop tool lumens, misting nozzles on the catheter, and delivery apparatuses including the catheter devices coupled to endoscopes such as bronchoscopes. Methods of use of the catheter devices and delivery apparatuses are also described.

Catheters and systems useful for delivery of material to the lung

The present embodiments provide systems and methods for deploying at least a portion of a stent. In one embodiment, the system comprises a cannula having an outer surface, and at least one coiled member having proximal and distal ends and a plurality of turns disposed therebetween. One of the proximal and distal ends of the coiled member is secured to the outer surface of the cannula, and the other of the proximal and distal ends of the coiled member is unsecured relative to the outer surface of the cannula. A portion of a stent is looped around the unsecured end of the coiled member and disposed within spacing between adjacent turns of the coiled member. Rotation of the cannula subsequently causes the portion of the stent to disengage from the coiled member.

Systems and methods for deploying a portion of a stent using at least one coiled member

The present embodiments provide stent-grafts. In one embodiment, a stent has proximal and distal ends, a plurality of strut segments disposed between the proximal and distal ends that enable expansion of the stent from a compressed state to a deployed state, and a series of distal apices disposed at the distal end of the stent. At least a portion of a first distal apex overlaps with graft material. First and second sutures are each coupled between a portion of the first distal apex and the graft material. The first and second sutures are positioned at different longitudinal zones that lack an axial overlap with one another.

Multi-level suture attachments for coupling a stent to graft material

A prosthesis delivery device and method of using the same is described. The delivery device comprises a rotatable inner cannula extending from a proximal end to a distal end with a prosthesis releasably coupled to the proximal end. A delivery handle assembly is disposed at the distal end of the delivery device. The handle comprises a first handle disposed about the inner cannula, a rotary dial rotatably disposed about a distal end of the first handle and a second handle disposed about at least a portion of the distal end of the first handle. The second handle is longitudinally moveable relative to the first handle between a first position wherein the sheath is coaxially disposed about the prosthesis and rotation of the rotary dial is prevented, and a second position wherein the sheath is retracted distally to expose at least a portion of the prosthesis and rotation of the dial is permitted.

Delivery device handle assembly for the sequential deployment of a prosthesis

The present invention provides apparatus and methods for treating a vascular condition by restoring patency to a vessel while reducing the likelihood that emboli become dislodged into the bloodstream. In a first embodiment, the apparatus comprises a graft having proximal and distal regions, a first support member attached to the distal region of the graft, and a second support member attached to the proximal region of the graft. The first and second support members may comprise first and second stents, respectively. The first stent is deployed distal to a vascular condition, and the second stent is deployed proximal to a vascular condition, such that the graft spans the length of the vascular condition to entrap emboli during treatment of the vascular condition. In an alternative embodiment, the graft is adapted to be everted to form a pocket adapted to entrap emboli dislodged during treatment of the vascular condition.

Apparatus and methods for in situ embolic protection

The present embodiments provide systems and methods for deploying at least a portion of a stent. In one embodiment, the system comprises a cannula having an outer surface, and a coiled member having proximal and distal ends and a plurality of turns disposed therebetween. At least a portion of the coiled member is secured to the outer surface of the cannula. A stent is releasably secured to a portion of the coiled member. A protective cage may encircle the coiled member.

An endoluminal prosthesis introducer may include a rotatable inner cannula including a proximal end. The introducer may include a proximal tip disposed at the proximal end of the inner cannula and including a distal end. The introducer may include a retaining member including an engaging member extending radially outward. The retaining member may be disposed about the proximal end of the inner cannula. In response to rotation of the inner cannula with respect to the retaining member, the proximal tip may be longitudinally movable relative to the engaging member between a retaining configuration and a releasing configuration. The proximal tip and the engaging member may be spaced from one another by a greater longitudinal distance in the releasing configuration than in the retaining configuration.

Endoluminal prosthesis introducer

An implantable graft device is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a woven fabric having warp yarns aligned in a first direction and weft yarns aligned in a second direction. The weft yarns are woven with the warp yarns. A portion of the warp yarns along the longitudinal axis of the graft body are not interwoven with the weft yarns, defining floating yarns having loops aligned in one of the first direction and the second direction. The device further comprises an expandable stent disposed circumferentially about the longitudinal axis and received through the loops of the floating yarns to attach the stent to the graft body.

Stent graft having floating yarns

An endoluminal prosthetic device for placement in a body lumen is formed by stitching stents to a graft. A first or anchoring stent is used for securing a graft made of biocompatible material that forms at least one lumen. There is also a second stent. The first and second stents each include a plurality of struts and apices between the struts. At least two of the apices in each of the first and second stents are secured to the graft by stitches. A running suture links at least one stitch of the first stent and one stitch of the second stent. The running suture linking the first stent and the second stent adds strength to the stitches and better secures the first stent to the device. The endoluminal prosthetic device may be used in an aortic vessel to treat stenoses or aneurysms.

Endoluminal prosthetic device

A method for producing a radially expandable prosthesis by cutting a pattern in a tubular member, which member has an outer diameter at least as great as the expanded diameter of the prosthesis.

Method of producing a radially expandable prosthesis

An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.

Endoluminal device with extracellular matrix material and methods

A system for anchoring an endoluminal prosthesis comprises a barb. The barb comprises a base, a retractable body extending distally from the base towards a distal anchor, and a hinge disposed between the base and the anchor and spaced apart from the base. The anchor pivots about the hinge between a retracted configuration and an extended configuration. Additional devices, systems, and methods are disclosed.

Flexible barb for anchoring a prosthesis

Growing community of inventors

Bloomington, IN, United States of America

Michael P DeBruyne