Endra Life Sciences Inc.

Duke University

Other

Volumetrics Medical Corp.

Thornton, Michael M.

Michael M Thornton

Jang Hwan Cho

Christopher Nelson Davis

Paul A Picot

Idan Steinberg

Jeremy Gill

Charlton Chen

Paolo Maccarini

Nathan John Muller

Aghapi Mordovanakis

Nigel Anthony Syrotuck

Martin Leandro Par

Scott Patrick Belanger

Amy L Sitzler

Dean Zahn Douthat

Richard Moss

Victor Motov

Dmitry V Vasilenko

Laura Karik

Timothy Sang-Ook Park

Christine Park

Kai Erik Thomenius

Jonathan M Rubin

Brian Rutt

Simone Winkler

Zackary Marc Mumm

Amanda Margaret Barnes

Jordan Sengenberger

Christopher Bull

Stanley Emil Jelic

Dima Shmidov

A radio frequency applicator, including a waveguide having a first interior surface comprising a first aperture, a second interior surface opposing the first interior surface, a third interior surface adjacent to the first and second interior surfaces, a fourth interior surface opposing the third interior surface, and a fifth interior surface perpendicular to the first, second, third, and fourth interior surfaces, an aperture antenna, a solid dielectric insert within the waveguide, the solid dielectric insert having a second aperture formed therethrough that is configured for alignment with the first aperture, an RF connector, configured to receive generated RF energy pulses, at least one planar-shaped shim, having a third aperture therethrough configured to align with the first and second apertures, and a radio frequency feed pin connected to the RF connector, disposed within the first, second, and third apertures and affixed to the second interior surface of the waveguide.

Radio frequency applicator

A method for determining an electromagnetic field spatial distribution of a radio frequency (RF) antenna which includes the steps of emitting with the RF antenna, a plurality of RF energy pulses into a homogeneous medium; performing a plurality of thermoacoustic signal measurements of the plurality of RF energy pulses, wherein each of the thermoacoustic signal measurements is performed in a similar manner; utilizing a variance in the plurality of thermoacoustic signal measurements to generate a reconstructed pressure distribution for a volume located within the homogeneous medium; and calculating the RF antenna electromagnetic field spatial distribution within the volume based upon the reconstructed pressure distribution for the volume located within the homogeneous medium.

Method and system to determine radio frequency antenna electromagnetic field spatial distribution

A thermoacoustic measurement probe includes an open-ended hollow radio-frequency (RF) waveguide; at least two RF feeds positioned within the open-ended hollow RF waveguide, wherein each RF feed is configured to provide RF energy; and a thermoacoustic transducer, wherein the open-ended hollow RF waveguide, in the form of a sleeve, surrounds and is mechanically joined to the thermoacoustic transducer.

Thermoacoustic measurement probe

A thermoacoustic probe for a thermoacoustic imaging system, the probe including: a radio-frequency (RF) applicator having an insert, wherein the applicator is configured to transmit at least one radio frequency source; an integral electromagnetic matching and acoustic extinction layer having a substantially flat-planar side and a substantially convex side, wherein the substantially flat-planar side of the integral electromagnetic matching and acoustic extinction layer is coupled to the insert of the RF applicator; and an optical transducer coupled to the substantially convex side of the integral electromagnetic matching and acoustic extinction layer.

Thermoacoustic probe

A thermoacoustic probe for a thermoacoustic imaging system, the probe including: a radio-frequency (RF) applicator having an insert, wherein the applicator is configured to transmit at least one radio frequency source; an electromagnetic matching layer coupled to the insert of the RF applicator; an optical transducer that is coupled to the electromagnetic matching layer; and an acoustic matching layer that is coupled to the optical transducer.

A radio frequency applicator for a thermoacoustic imaging system is disclosed. The applicator includes, a waveguide with an internal radio frequency source, wherein the waveguide has an opening, an electromagnetic matching layer coupled to the waveguide and proximate to the opening, and an acoustic absorbing layer that is coupled to the matching layer.

Radio frequency applicator for a thermoacoustic imaging system

A thermoacoustic measurement probe may include an open-ended hollow radio-frequency (RF) waveguide; and a thermoacoustic transducer, wherein the open-ended hollow RF waveguide, in the form of a sleeve, surrounds and is mechanically joined to the thermoacoustic transducer.

A method for exchange of equipment performance data includes the steps of: obtaining performance data of a communicatively-insulated device; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a communicatively-enabled device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; initiating, by the communicatively-enabled device, a communications link with the remote server using the address string thereby to provide the performance data to the remote server; performing, by the remote server, analytics on the performance data; and sending historic device performance data and/or analytical results to a remote computing device and/or sending a link to the historic device performance data and/or analytical results to the remote computing device; wherein the communicatively-insulated device is packaging equipment and wherein obtaining the performance data comprises: running a calibration phantom through the packaging equipment; scanning the calibration phantom with a calibration unit; and using the calibration unit to generate a system status report identifying one or more operational parameters of the packaging equipment.

Methods and systems for exchange of equipment performance data

A method for exchange of equipment performance data includes the steps of: obtaining performance data of a communicatively-insulated device; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a communicatively-enabled device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; initiating, by the communicatively-enabled device, a communications link with the remote server using the address string thereby to provide the performance data to the remote server; performing, by the remote server, analytics on the performance data; and sending historic device performance data and/or analytical results to a remote computing device and/or sending a link to the historic device performance data and/or analytical results to the remote computing device; wherein the communicatively-insulated device is medical imaging equipment and wherein obtaining the performance data comprises scanning a phantom using the medical imaging equipment and/or acquiring medical imaging equipment sensor data and generating a system status report identifying one or more operational parameters of the medical imaging equipment.

A system utilizing thermoacoustic imaging to estimate tissue temperature within a region of interest that includes an object of interest and a reference which are separated by at least one boundary located at least at two boundary locations. The system uses a thermoacoustic imaging system that includes an adjustable radio frequency (RF) applicator configured to emit RF energy pulses into the tissue region of interest and heat tissue therein and an acoustic receiver configured to receive multi-polar acoustic signals generated in response to heating of tissue in the region of interest; and one or more processors that are able to: process received multi-polar acoustic generated in the region of interest in response to the RF energy pulses to determine a peak-to-peak amplitude thereof; and calculate a temperature at the at least two boundary locations using the peak-to-peak amplitudes of the multi-polar acoustic signals and a distance between the boundary locations.

System for monitoring tissue temperature

A method for manufacturing a radio frequency (RF) applicator which includes covering a ceramic insert with a coating, wherein the ceramic insert has dimensions that substantially match an internal volume of an open-ended, hollow waveguide, and wherein the ceramic insert has a recess therein configured to accept a radio frequency emitter, heating the waveguide to a temperature that is above a melting point of the coating, placing the coated ceramic insert into the internal volume of the heated waveguide, wherein the internal volume is completely filled except for the recess, and cooling the waveguide, ceramic insert, and coating to a temperature below the melting point of the coating so that the coating solidifies and fills gaps between facing surfaces of the insert and the waveguide.

Method for manufacturing a radio frequency applicator

A method for exchange of equipment performance data includes the steps of: obtaining performance data of a communicatively-insulated device; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a communicatively-enabled device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; and initiating, by the communicatively-enabled device, a communications link with the remote server using the address string thereby to provide the performance data to the remote server.

A method for an exchange of equipment performance data including the steps of: obtaining performance data of a device not having internet connectivity; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a computing device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; initiating, by the computing device, an internet connection with the remote server using the address string thereby to provide the performance data to the remote server; performing, by the remote server, analytics on the device performance data; and sending historic device performance data and/or analytical results to a remote computing device and/or sending a link to the historic device performance data and/or analytical results to the remote computing device; wherein the device is packaging equipment and wherein obtaining the performance data comprises: running a calibration phantom through the packaging equipment; scanning the calibration phantom with a calibration unit; and using the calibration unit to generate a system status report identifying one or more operational parameters of the packaging equipment.

A method for an exchange of equipment performance data including the steps of: obtaining performance data of a device not having internet connectivity; converting the performance data into a scannable code; capturing an image of the scannable code; decoding the scannable code using a computing device to extract an address string encoded in the scannable code, the address string comprising an address of a remote server and the performance data; initiating, by the computing device, an internet connection with the remote server using the address string thereby to provide the performance data to the remote server; performing, by the remote server, analytics on the device performance data; and sending historic device performance data and/or analytical results to a remote computing device and/or sending a link to the historic device performance data and/or analytical results to the remote computing device; wherein the device is medical imaging equipment and wherein obtaining the performance data comprises scanning a phantom using the medical imaging equipment and generating a system status report identifying one or more operational parameters of the medical imaging equipment.

A method and system for optimizing RF energy delivery to a tissue ROI with a thermoacoustic system includes directing with a RF applicator, RF energy pulses into the tissue ROI having an object of interest and a reference separated by a boundary; detecting with a thermoacoustic transducer, a multi-polar thermoacoustic signal generated at the boundary in response to the RF energy pulses and processing the multi-polar acoustic signal to determine a peak-to-peak amplitude; detecting with the thermoacoustic transducer, an artifact multi-polar thermoacoustic signal generated at a location other than the boundary and processing it to determine a peak-to-peak amplitude; utilizing an electromagnetic model coupled with a model of patient anatomy to place dielectric or conducting materials near the thermoacoustic transducer or the RF applicator to optimize a signal-to-noise ratio of the multi-polar thermoacoustic signal generated at the boundary or minimize the artifact multi-polar thermoacoustic signal generated at a location other than the boundary; and directing with the RF applicator, RF energy pulses into the ROI for a thermoacoustic measurement and determine a parameter of the object of interest.

Growing community of inventors

London, Canada

Michael M Thornton