Molecular Devices Corporation

Caliper Technologies Corporation

Caliper Life Sciences, Inc.

Michael M Lacy

Calvin Y Chow

Dean G Hafeman

Mark Wechsler

Roger A Kaye

David G Ogle

Kimberly L Crawford

Howard Hunter Barney

Calvin Y H Chow

Colin B Kennedy

Morten Juel Jensen

Viola T Kung

Robert E Nagle

Gillian M Humphries

Rick T Smethers

Vladimir J Drbal

Jonathan Briggs

Thomas L Smith

Suresh N Mehta

Lev Leytes

Gregory L Kirk

Debra A Ross

Paul Hayter

George Pontis

A microfluidic controller and detector system and method for performing screening assays are disclosed. The microfluidic controller and detector system comprises a fluidic chip that includes at least two intersecting channels and a detection zone, a fluid direction system comprising an electrical interface configured for electrical contact with the at least two intersecting channels, an optics block having an objective lens disposed adjacent the detection zone, and a control system coupled to the optics block and adapted to receive and analyze data from the optics block. The electrical interface generally includes electrodes configured for electrical contact with the intersecting channels and coupled to electrode channels for supplying electrical input to the electrodes. A reference channel is optionally provided to calibrate the electrode channels.

Microfluidic controller and detector system with self-calibration

The present invention relates to a photometric device for measuring optical parameters. The invention functions in the ultraviolet light range through use of a monochromator and splits the test light in multiple channels by a rotor assembly, including a mirror.

Photometric device

This invention encompasses a work station for conducting assays which comprises filtering assembly, a slide reading assembly, and a slide with a porous filter membrane wherein the slide has a means for aligning the slide within the filter assembly to filter reagents on predetermined portions of the porous filter membrane and also to position the slide in the slide reading assembly so that detection will occur in those same predetermined locations.

Analytical work station

A multibeam photometric measuring device includes a light assembly comprising a single modulated light source along with a filter assembly for passing only a desired band of wavelengths and an optical system for suitably focusing light from the light source. A plurality of light transmitting means accept light and transmit it individually to each of the plurality of sites disposed on a multi-well sample plate. Enhancement of color distribution resulting from chromogenic reactions is provided by automatic agitation of the reacting agents within the sample wells before a reading is taken at each of the sampling intervals of a kinetic measurement sequence.

Single source multi-site photometric measurement system

A multibeam photometric measuring device includes a single light source along with a filter assembly for passing only a desired band of wavelengths and an optical system for suitably focusing light from the light source. Light is transmitted individually to each of a plurality of sites disposed on a multi-well sample plate. Enhancement of color distribution is provided by automatic agitation of the reacting agents within the sample wells before a reading is taken at each of the sampling intervals of a kinetic measurement sequence.

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Ben Lomond, CA, United States of America

Michael M Lacy