University of Oregon

Other

University of Montana

State of Oregan Acting by and Through the State Board of Higher Education on Behalf of the University of Oregan

Michael M Haley

Darren W Johnson

Michael Pluth

Sean Fontenot

Aaron G Fix

Daniel T Chase

Gabriel E Rudebusch

Orion B Berryman

Jeff Engle

Calden Carroll

Charles A Johnson

Chris Vonnegut

Justin Dressler

Joshua Barker

Brad Rose

Jessica Lohrman

John Andrew Berglund

M Bryan Warf

Catherine Matthys

Cameron L Hilton

Asia M Riel

Calden N Stimpson

Airlia Shonkwiler

Michelle Watt

Daniel A Decato

Darren Johnson

A device that includes a polymeric layer, wherein the polymeric layer comprises (A) a polymer and, incorporated within the polymeric layer, (B) a compound, or a protonate or salt thereof, wherein the compound, or a protonate or salt thereof, has a structure that includes at least one moiety configured for reversible, non-covalent binding of the anionic sulfide species.

Device for detecting hydrosulfide

A method for detecting for the presence of HS or HSanion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: 

Synthetic receptors for hydrosulfide

A compound, or a protonate or salt thereof, of formula I:  is an aryl or heteroaryl ring; and are not respectively.

Fluorescent halogen bonding arylethynyl scaffolds for anion recognition

Disclosed herein are polycyclic aromatic compound embodiments and methods of making and using such compounds. In some embodiments, the polycyclic aromatic compounds comprise an indenoindenodi(benzothiophene) skeleton. The polycyclic aromatic compound embodiments can be used in a variety of devices, such as electronic and/or electrooptical devices.

Polycyclic aromatic compound embodiments and methods of making and using the same

Disclosed embodiments concern a phosphorus-containing heterocyclic compound according to the formula One exemplary compound is Certain embodiments fluoresce with excitation by light. The compounds are useful as fluorescent probes and as bioisosteres. In some embodiments, the compounds are bioisosteres of alpha-quinolones. Also disclosed is a method for making the compounds.

Phosphorus-containing heterocycles and a method for making and using

A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; Rand Rare each independently H; optionally substituted alkyl; optionally substituted aralkyl; acyl; phosphonyl; &#x2014;SOR; &#x2014;C(O)R; &#x2014;C(O)OR; &#x2014;C(O)NRR; &#x2014;C(O)CHR; or &#x2014;C(S)&#x2014;NRR; &#x2014;S(O)R20; or &#x2014;SONRR, wherein R-Rare each independently H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted aryl, or &#x2014;C(O)R, wherein Ris H, optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and each Ris independently optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, amide; amino; or nitro.

Tripodal nitrate receptor

Disclosed herein are host or receptor compounds that bind targets of interest. In one embodiment the compounds bind ions, such as metal ions. A compound, or a protonate or salt thereof, having the formula of: 

Phenylacetylenes

Disclosed herein are embodiments of thieno-containing compounds suitable for use in electrical devices and/or electrooptical device. Also disclosed herein are methods of making the disclosed compounds, with particular embodiments of the method concerning a novel dione intermediate that may be used to make particular embodiments of the thieno-containing compounds.

Thieno-containing compounds and processes and uses thereof

A compound having a structure represented by formula I: wherein each Ris independently H, alkynyl or substituted alkynyl;

Diindenoanthracene and diindenopentacene

Indenofluorenes that include at least two alkynyl-containing substituents.

Alkynyl-substituted indenofluorenes useful in electronic and electro-optical devices

Heteroatomic indenofluorenes

A compound, or a salt thereof, having the formula  

Tunable phenylacetylene hosts

Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.

Uses of pentamidine and related compounds

Disclosed herein is a class of tunable phenylacetylene compounds as well as compositions and methods for their use as host compounds for ligand binding. In certain examples the hosts report binding events by exhibiting altered spectroscopic properties, such as different fluorescent emission spectra.

Growing community of inventors

Eugene, OR, United States of America

Michael M Haley