Medlogic Global Corporation

Flowers Park Ltd.

Michael M Byram

Richard J Greff

Leonard V Barley, Jr

Patrick J Tighe

Ian N Askill

Robert Goebel

Richard T VanRyne

A cyanoacrylate adhesive is applied onto intact surface skin areas prone to ulceration so as to inhibit formation of surface skin ulcers.

Methods for inhibiting skin ulceration by use of cyanoacrylate adhesives

Antimicrobial cyanoacrylate compositions are applied to suturable wound surfaces to close the wound surface.

Methods for closing suturable wounds by use of cyanoacrylate ester compositions comprising an antimicrobial agent

Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably an acyl trialkyl citrate wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms), and SO,as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.

Cyanoacrylate adhesive compositions

Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.

Cyanoacrylate compositions comprising an antimicrobial agent

Disclosed are methods for the application of a cyanoacrylate/anti-microbial composition over mammalian skin surfaces to peri-wound and peri-mucosal areas. The composition can also be applied over medicament that has been applied onto the skin surface.

Application of cyanoacrylate/anti-microbial compositions to the

Disclosed are methods for draping a surgical site prior to surgery. Specifically, the methods of this invention involve the in situ formation of a cyanoacrylate polymeric drape on the skin surface of a patient peripheral to the surgical site. Surgery is then conducted at the surgical site.

Methods for draping surgical sites using peripheral cyanoacrylate drapes

Disclosed are cyanoacrylte compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine coning antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacryate film on mammalian skin.

Cyanoacrylate compostions comprising an antimicrobial agent

Disclosed are methods for draping a surgical incision site prior to surgery. Specifically, the methods of this invention involve the in situ formation of a cyanoacrylate polymeric drape over the skin surface at the surgical incision site. An incision is then made through this surface and the surgery is then conducted through the incision.

Methods for draping surgical incision sites

Antimicrobial cyanoacrylate compositions are applied to non-suturable, superficial wound surfaces. In situ polymerization of the cyanoacrylate ester provides for a polymeric film over the wound which promotes wound healing and retards infection of the wound.

Methods for treating non-suturable, superficial wounds by use of

Disclosed are methods for inhibiting acute radiation-induced skin damage during treatment of a patient with ionizing radiation by application of a layer of biocompatible polymer to the skin surface prior to exposure of the surface to ionizing radiation.

Methods to inhibit acute radiation-induced skin damage

Disclosed are methods for inhibiting late radiation-induced skin damage during treatment of a patient with ionizing radiation by application of a layer of biocompatible polymer to the skin surface prior to exposure of the surface to ionizing radiation.

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Colorado Springs, CO, United States of America

Michael M Byram