Musculoskeletal Transplant Foundation

The Methodist Hospital

Michael Locarno

Manh-Dan Ngo

Bryan Choi

Aldona Jedrysiak Spiegel

Gregory P Adams

Todd J Nilsen

Evangelia Chnari

Antonio M Bunce

Bryan J Choi

Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.

Soft tissue repair and methods for preparing same

A dermal tissue allograft includes a dermal matrix having a profile including first and second vertices, a first imaginary axis extending between the first and second vertices, a first peripheral edge extending along a continuous path from the first vertex to the second vertex on a first side of the first imaginary axis, and a second peripheral edge extending along a continuous path from the first vertex to the second vertex on a second side of the first imaginary axis. The first peripheral edge includes an apogee, a convex portion, and a concave portion. The convex and concave portions meet at a transition point located on the first peripheral edge between its apogee and the second vertex. The second peripheral edge includes an apogee and is convex. The second perpendicular distance is greater than the first perpendicular distance. The dermal matrix has a substantially uniform thickness across its profile.

Asymmetric tissue graft

Soft tissue repair allografts and methods for preparing same

Growing community of inventors

Kinnelon, NJ, United States of America

Michael Locarno