Inari Agriculture Technology, Inc.

Inari Agriculture, Inc.

Michael Lee Nuccio

Michael Andreas Kock

Joshua L Price

Davide Sosso

Yajie Niu

John Patrick Casey, Jr

Randall William Shultz

Tomás Cermák

Maria Margarita D Unson

Daniel Rodriguez Leal

Richard Bailey Flavell

Jennifer A Raji

Alexandra Elata

Eva Konecna

Frédéric Van Ex

Barry Andrew Martin

David J Segal

Jonathan Dallas George Jones

Tomáš Cermák

Mircea Achiriloaie

INIR12 TRANSGENIC MAIZE

Compositions containing chimeric RNA molecules which comprise meristem targeting sequences that are fused to RNA cargo sequences that include gene editing molecules are provided. Methods of using the compositions to efficiently edit plant genomes without intervening tissue culture steps are also provided. The solutions described here relate to engineered RNA molecules useful in producing plants with altered genomes. As such, it relates to substantially purified compositions, vectors, systems, as well as genomes of plants.

Genomic alteration of plant germline

Transgenic INIR20 soybean plants comprising modifications of the MON87701 soybean locus which provide for facile excision of the modified MON87701 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

INIR20 transgenic soybean with junction polynucleotide deletions

Transgenic INHT27 soybean plants comprising modifications of the DAS68416-4 soybean locus which provide for facile excision of the modified DAS68416-4 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

Modified excisable DAS68416-4 soybean transgenic herbicide resistance locus

Transgenic INIR6 maize plants comprising modifications of the DP-4114 maize locus which provide for facile excision of the modified DP-4114 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

INIR6 transgenic maize

Transgenic INHT30 soybean plants comprising modifications of the MON87708 soybean locus which provide for facile excision of the modified MON87708 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

Modified excisable MON87708 soybean transgenic herbicide resistance locus

The disclosure relates to improvements in methods for efficient editing of two or more endogenous tomato genes by insertion of one or more single stranded DNA donor molecules that are not homologous to the insertion sites in the tomato genome.

Methods for efficient tomato genome editing

The disclosure relates to precise modifications in wheat plant genomes including the heterologous integration of nucleic acid sequences that include a regulatory element at a predetermined locus. Also provided are wheat cells, wheat plants, wheat seeds, and processed wheat products comprising the modified wheat genomes.

Heterologous integration of regulatory elements to alter gene expression in wheat cells and wheat plants

Transgenic INIR19 soybean plants comprising modifications of the DAS81419 soybean locus which provide for facile excision of the modified DAS81419 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

Modified excisable DAS81419-2 soybean transgenic insect resistance locus

Modified excisable MON87701 soybean transgenic insect resistance locus

Transgenic INIR11 maize plants comprising modifications of the MON89034 maize locus which provide for facile excision of the modified MON89034 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

Modified excisable MON89034 transgenic maize insect resistance locus

The disclosure relates to improvements in methods for efficient editing of two or more endogenous soybean genes by insertion of one or more single stranded DNA donor molecules that are not homologous to the insertion sites in the soybean genome.

Methods for efficient soybean genome editing

Transgenic INHT31 soybean plants comprising modifications of the MON89788 soybean locus which provide for facile excision of the modified MON89788 transgenic locus or portions thereof, methods of making such plants, and use of such plants to facilitate breeding are disclosed.

Excisable INHT31 transgenic soybean glyphosate tolerance locus

Plant cells and related systems, methods, and compositions for improving the capacity of the plant cells to regenerate embryogenic plant tissues, plant organs, and whole plants are provided. Such plant cells and related systems, methods, and compositions provide for increased expression of the endogenous morphoregulators BABYBOOM (ODP2) and/or WUSCHEL2 (WUS2).

Plant transformation

Transgenic INIR17 maize plants comprising an ecry3.1Ab expression cassette linked to a secondary nopaline synthase terminator element which lack a selectable marker gene and/or which comprise modifications that provide for facile excision of the INIR17 transgenic locus from the maize plant genome are provided. Genomic DNA of INIR17 transgenic plants, detection of INIR17 plants and products thereof, methods of making INIR17 plants, and use of INIR17 plants to facilitate breeding are disclosed.

Growing community of inventors

Salem, NH, United States of America

Michael Lee Nuccio