Other

Entasis Therapeutics, Inc.

Michael L Huband

Disclosed are methods for treating various bacterial infections with (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a][1,2]oxazolo[4,5-g]quinoline-5,5&#x2032;-pyrimidine]-2&#x2032;,4&#x2032;,6&#x2032;(1&#x2032;H,3&#x2032;H)-trione, or a pharmaceutically acceptable salt thereof.

Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections

A needle-protecting assembly adapted to be mounted upon the discharge extremity of the barrel of a conventional hypodermic syringe has a cylindrical hub adapted to hold a cannula needle of conventional construction. A transparent cylindrical sheath slidingly engages the hub. The sheath has a longitudinal slot and communicating detent, and a locking aperture. A tab radially emergent from the hub can be caused to engage the detent, slot or locking aperture, achieving respectively, a storage state where the sheath extends forwardly of the tip of the needle, a use state where the tip of the needle extends forwardly of the sheath, and an irreversibly locked disposal state wherein the sheath is forward of the tip of the needle.

Protective needle assembly for hypodermic syringe

A protective needle assembly adapted to be mounted upon the discharge extremity of the barrel of a conventional hypodermic syringe has a cylindrical hub that holds an axially aligned cannula needle. A transparent cylindrical sheath slidingly engages the hub. The sheath has a longitudinal slot and communicating detent, and a locking aperture. A tab radially emergent from the hub can be caused to engage the detent, slot or locking aperture, achieving respectively, a storage state where the sheath extends forwardly of the tip of the needle, a use state where the tip of the needle extends forwardly of the sheath, and an irreversibly locked disposal state wherein the sheath is forward of the tip of the needle.

Growing community of inventors

Richmond, VA, United States of America

Michael L Huband