Roche Diagnostics Operations, Inc.

Hitachi High-tech Corporation

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Michael Kuehnl

Yoshihiro Yamashita

Reinhold Kraemer

Koshin Hamasaki

Takaaki Hagiwara

Michaela Windfuhr

Guenter Ziegler

Herbert Buschek

Yuichiro Ota

Klaus Erler

Uwe Mertsch

Roland Ihrig

Johannes Stoeckel

Marion Borchers

Maria Cully

Heike Guggemos

The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.

Automatic analysis apparatus

A method of monitoring detection of an analyte in a liquid sample using a measuring cell, the measuring cell comprising a working electrode for excitation of electrochemiluminescence in the liquid sample, an optical detector for detecting the excited electrochemiluminescence, the excitation and detection being performed in an measurement cycle, the measurement cycle comprising transporting the liquid sample via a transport path to the working electrode using a support liquid, the method comprising: coupling light of a light source into the transport path during part of the measurement cycle, the transport path forming a light guide between the light source and the optical detector, detecting the coupled light by the optical detector, analyzing the detected light for a gas bubble in the transport path, providing a measurement state if the result of the analysis deviates from a target state regarding the presence of a gas bubble in the transport path.

Method of monitoring an operation of detection of an analyte in a liquid sample

There is provided a system for the preparation of liquids from at least one solid and at least one liquid phase. The system is composed of a vessel in which the solid or solids are located and a drying chamber which is connected to the vessel or can be connected to the vessel. The drying chamber is separated from the vessel interior by a separating means which is permeable to water vapour but is impermeable to liquids. The system is suitable for the production of liquids from moisture-sensitive solids. These solids can be stored in the vessel since the air humidity in the interior is lowered by the desiccant. The preparation of the liquid by addition of a liquid phase can be carried out in one and the same vessel since the desiccant is separated from the vessel interior.

Apparatus with desiccant chamber and method of using

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Mannheim, Germany

Michael Kuehnl