Boehringer Ingelheim International Gmbh

Boehringer Ingelheim Kg

Boehringer Ingelheim Pharma Gmbh & Co Kg

Michael Krueger

Elmar Mock

Johannes Geser

Michael Spallek

Herbert Wachtel

Antonino Lanci

Burkhard Metzger

Andre Klopfenstein

Achim Moser

Hubert Kunze

Bernd Zierenberg

Bernhard Freund

Michael Trunk

Joerg Schiewe

André Klopfenstein

Regis Cartier

Marc Egen

Herbert Kunze

Burkhard P Metzger

A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers&#x2014;typically one, two or three&#x2014;to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.

Medicine dispensation device

A device () for determining the solution rate and release kinetics of aerosol formulations comprises an inhaler () connected to a cascade impactor (), wherein a membrane () is disposed on a filter plate of the cascade impactor (), and an air-liquid model system with a device for collecting measured data.

Device and method for determining the properties of aerosol formulations

The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches () for holding a medicament are formed as depicted in exemplary FIG.. The foil strip comprises for transporting the strip openings () on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.

Medicaments magazine, and a device and method for opening it; multi-dose powder inhaler

A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece () and an air channel () connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (') can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening () which communicates with a control opening (), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.

Medicament dispensing device, medicament magazine therefor and method of removing a medicament from a medicament chamber

The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips as depicted in exemplary FIGS.and. The medicament chambers have an internal structure () which comprises in its interior a space for receiving a powdered medicament and stabilizes this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilizing function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.

Medicaments magazine for an inhaler, and a multi-dose powder inhaler

The invention relates to ethanol-containing pharmaceutical preparations for the production of propellant-free aerosols.

Stable pharmaceutical budesonide preparation for producing propellant-free aerosols

A stable ethanolic solution of budesonide is disclosed, which solution is suitable for use in nebulizers, together with a process for making such stable solution.

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Ingelheim, Germany

Michael Krueger