The Chinese University of Hong Kong

Michael Kenneth Chan

Yi-Ping Ho

Md Habibur Rahman

Marianne Lee

Ming Ming Marianne Lee

Chung Hong Nathaniel Wong

Bradley Heater

Zaofeng Yang

A module of microfluidic device used for applying shear stress to cells () in order to deliver payloads () to the cells (). The module includes cross junction modules (), serpentine modules and squeezing-relaxing modules (). The devices and related methods result in increased payload () delivery and reduced loss in cell () viability.

Systems and methods for controlled membrane disruption

Provide is a novel system for immobilizing recombinantly produced proteins by entrapping them in crystals of co-expressed proteins that are capable of self-crystallization. Related compositions and as well as methods of making and using the immobilized proteins are also described.

In vivo immobilization of proteins

It provides novel fusion proteins that are capable of self-crystallization and exhibit improved physical properties such as enhanced tolerance to organic solvents and increased thermostability. Polynucleotides encoding the fusion proteins as well as methods of making and using such fusion proteins are also described.

Fusion proteins with improved properties

Growing community of inventors

Kowloon Tong, China

Michael Kenneth Chan